ArticlePLoS pathogens2021
The Pleiades are a cluster of fungal effectors that inhibit host defenses.
Article in PLoS pathogens, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 38 citations in OpenAlex.
- Article
- CONSERVATION AND DIVERGENCE WITHIN THEbioRxiv : the preprint server for biology · 2026Article
- Pathogenic fungus Ustilago maydis exploits the lateral root regulators to induce pluripotency in maize shoots.The New phytologist · 2026Article
- Plant-microbe interactions through a lens: tales from the mycorrhizosphere.Annals of botany · 2024Review
- Manipulation of Auxin Signaling by Smut Fungi during Plant Colonization.Journal of fungi (Basel, Switzerland) · 2023Review
- Surface frustration re-patterning underlies the structural landscape and evolvability of fungal orphan candidate effectors.Nature communications · 2023Article
- Combination of in vivo proximity labeling and co-immunoprecipitation identifies the host target network of a tumor-inducing effector in the fungal maize pathogen Ustilago maydis.Journal of experimental botany · 2023Article
- Foxtail mosaic virus: A tool for gene function analysis in maize and other monocots.Molecular plant pathology · 2023Review
- The nuclear effector MoHTR3 of Magnaporthe oryzae modulates host defence signalling in the biotrophic stage of rice infection.Molecular plant pathology · 2023Article
- Co-immunoprecipitation-Based Identification of Effector-Host Protein Interactions from Pathogen-Infected Plant Tissue.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Identification of a Novel Lipase with AHSMG Pentapeptide in Hypocreales and Glomerellales Filamentous Fungi.International journal of molecular sciences · 2022Article
- Effector-mediated relocalization of a maize lipoxygenase protein triggers susceptibility to Ustilago maydis.The Plant cell · 2022Article
- Plant-microbe interactions in the apoplast: Communication at the plant cell wall.The Plant cell · 2022Article
- A chromosome-scale genome assembly of the tomato pathogenMicrobial genomics · 2022Article
- TOPLESS promotes plant immunity by repressing auxin signaling and is targeted by the fungal effector Naked1.Plant communications · 2022Article
- Predication of the Effector Proteins Secreted byJournal of fungi (Basel, Switzerland) · 2022Article
- Virus-Mediated Protein Overexpression (VOX) in Monocots to Identify and Functionally Characterize Fungal Effectors.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Construction and analysis of gene co-expression network in the pathogenic fungusFrontiers in microbiology · 2022Article
- A Novel Core Effector Vp1 Promotes Fungal Colonization and Virulence ofJournal of fungi (Basel, Switzerland) · 2021Article
- Population Genomics of the Maize Pathogen Ustilago maydis: Demographic History and Role of Virulence Clusters in Adaptation.Genome biology and evolution · 2021Article
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Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
Abstract
Biotrophic plant pathogens secrete effector proteins to manipulate the host physiology. Effectors suppress defenses and induce an environment favorable to disease development. Sequence-based prediction of effector function is impeded by their rapid evolution rate. In the maize pathogen Ustilago maydis, effector-coding genes frequently organize in clusters. Here we describe the functional characterization of the pleiades, a cluster of ten effector genes, by analyzing the micro- and macroscopic phenotype of the cluster deletion and expressing these proteins in planta. Deletion of the pleiades leads to strongly impaired virulence and accumulation of reactive oxygen species (ROS) in infected tissue. Eight of the Pleiades suppress the production of ROS upon perception of pathogen associated molecular patterns (PAMPs). Although functionally redundant, the Pleiades target different host components. The paralogs Taygeta1 and Merope1 suppress ROS production in either the cytoplasm or nucleus, respectively. Merope1 targets and promotes the auto-ubiquitination activity of RFI2, a conserved family of E3 ligases that regulates the production of PAMP-triggered ROS burst in plants.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.