Evidence map›Paper›PMID 34166224›Full record

ArticleAging2021

The consequences of a high-calorie diet background before calorie restriction on skeletal muscles in a mouse model.

Martin Maldonado, Jianying Chen, Yang Lujun, Huiqin Duan, Mazhar Ali Raja, Ting Qu, Tianhua Huang, Jiang Gu, Ying Zhong

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Martin MaldonadoChengdu Jinxin Institute of Reproductive Medicine and Genetics, Chengdu Jinjiang Hospital for Maternal and Child Health Care, Chengdu 610066, China.
Jianying ChenChengdu Jinxin Institute of Reproductive Medicine and Genetics, Chengdu Jinjiang Hospital for Maternal and Child Health Care, Chengdu 610066, China.
Yang LujunTranslational Medical Center, Second Affiliated Hospital of Shantou University Medical College, Shantou 515041, Guangdong, P.R. China.
Huiqin DuanChengdu Jinxin Institute of Reproductive Medicine and Genetics, Chengdu Jinjiang Hospital for Maternal and Child Health Care, Chengdu 610066, China.
Mazhar Ali RajaChengdu Jinxin Institute of Reproductive Medicine and Genetics, Chengdu Jinjiang Hospital for Maternal and Child Health Care, Chengdu 610066, China.
Ting QuChengdu Jinxin Institute of Reproductive Medicine and Genetics, Chengdu Jinjiang Hospital for Maternal and Child Health Care, Chengdu 610066, China.
Tianhua HuangChengdu Jinxin Institute of Reproductive Medicine and Genetics, Chengdu Jinjiang Hospital for Maternal and Child Health Care, Chengdu 610066, China.
Jiang GuChengdu Jinxin Institute of Reproductive Medicine and Genetics, Chengdu Jinjiang Hospital for Maternal and Child Health Care, Chengdu 610066, China.
Ying ZhongChengdu Jinxin Institute of Reproductive Medicine and Genetics, Chengdu Jinjiang Hospital for Maternal and Child Health Care, Chengdu 610066, China.
Maternal and Child Health Hospital of Sichuan Province · CNShantou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The beneficial effects of calorie restriction (CR) are numerous. However, there is no scientific evidence about how a high-calorie diet (HCD) background influences the mechanisms underlying CR on skeletal muscles in an experimental mouse model. Herein we present empirical evidence showing significant interactions between HCD (4 months) and CR (3 months). Pectoralis major and quadriceps femoris

Indexed as

Caloric RestrictionDietAdenylate KinaseAdiponectinAnimalsBiomarkersDisease Models, AnimalDNA, MitochondrialFemaleGene DosageGene Expression RegulationLipidsMiceMice, Inbred ICRMuscle, SkeletalOrganelle BiogenesisAdenylate KinaseAdiponectinBiomarkersDNA, MitochondrialLipidsReceptors, AdiponectinSirtuin 1TelomeraseTOR Serine-Threonine Kinasesadiponectincalorie-interventionmitochondriasirtuinsskeletal muscle

Identifiers

PMID34166224
PMCPMC8266348
OpenAlexW3177172682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.