ArticleJournal of primary care & community health
Mental Stress, Anxiety and Depressive Symptoms and Interleuken-6 Level among Healthcare Workers during the COVID-19 Pandemic.
Article in Journal of primary care & community health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 19 citations in OpenAlex.
- From screens to serenity: evaluating the effect of digital detox on mental and physiological health.BMC medical education · 2025Trial
- Psychological Stress and Male Infertility: Oxidative Stress as the Common Downstream Pathway.Biomedicines · 2026Review
- Psychological and Physiological Assessment of Distress Among Public Healthcare Workers During Pandemic Control Efforts.Healthcare (Basel, Switzerland) · 2026Article
- Sex-specific regulation of microglial MyD88 in HMGB1-Induced anxiety phenotype in mice.Neurobiology of stress · 2025Article
- Microglial MyD88-dependent pathways are regulated in a sex-specific manner in the context of HMGB1-induced anxiety.bioRxiv : the preprint server for biology · 2024Article
- Association between body mass index and mental health among nurses: a cross-sectional study in China.BMC health services research · 2024Article
- The role of torso stiffness and prediction in the biomechanics of anxiety: a narrative review.Frontiers in sports and active living · 2024Review
- Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study aimed to evaluate the interleukin-6 (IL-6) levels and its relationship to stress, anxiety, and depressive symptoms among healthcare workers (HCWs) compared to controls during the COVID-19 pandemic.
methodsA total of 80 HCWs in Suez Canal University Hospital in Ismailia, Egypt, and 80 controls were analyzed during the COVID-19 pandemic. The Depression, Anxiety and Stress Scale (DASS 21) questionnaire was used, and serum IL-6 level was determined in both groups.
resultsIL-6 levels were high in 81.2% (65) of HCWs compared to 36% (45) of controls (
conclusionThe IL-6 level and DASS score were higher in HCWs compared to those in controls during the COVID-19 pandemic. The type of work as a healthcare staff, stress, and irregular or night shift were predictors of increased IL-6 levels.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.