Evidence map›Paper›PMID 34166069›Full record

ArticleCirculation research2021

Vascular and Lymphatic Malformations: Perspectives From Human and Vertebrate Studies.

Harish P Janardhan, Sherin Saheera, Roy Jung, Chinmay M Trivedi

Open access · bronzeAbstract read
In one paragraph

Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. [Cystic lymphangioma of the penis in an adult: A case report].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Lymphatic System Development and Function.Current cardiology reports · 2024
    Review
  8. Vascular malformations in the thighs of identical twin sisters.Journal of vascular surgery. Venous and lymphatic disorders · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Cystic hygroma of the neck - case report.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Harish P JanardhanDivision of Cardiovascular Medicine (H.P.J., S.S., R.J., C.M.T.), University of Massachusetts Medical School, Worcester.
Sherin SaheeraDivision of Cardiovascular Medicine (H.P.J., S.S., R.J., C.M.T.), University of Massachusetts Medical School, Worcester.
Roy JungDivision of Cardiovascular Medicine (H.P.J., S.S., R.J., C.M.T.), University of Massachusetts Medical School, Worcester.
Chinmay M TrivediDivision of Cardiovascular Medicine (H.P.J., S.S., R.J., C.M.T.), University of Massachusetts Medical School, Worcester.
University of Massachusetts Chan Medical School · US

Funding

Epigenetic regulation of lymphatic developmentR01HL141377 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI TRIVEDI, CHINMAY M · 2018 to 2025
$4.1M
Regulation of Cardiac Development by Chromatin Modifying EnzymesR01HL118100 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI TRIVEDI, CHINMAY M · 2013 to 2022
$3.7M
NHLBI NIH HHS R01 HL118100NHLBI NIH HHS R01 HL141377
6 · The paper itself

Abstract

Vascular malformations, affecting ≈1% to 1.5% of the population, comprise a spectrum of developmental patterning defects of capillaries, arteries, veins, and/or lymphatics. The majority of vascular malformations occur sporadically; however, inherited malformations exist as a part of complex congenital diseases. The malformations, ranging from birthmarks to life-threatening conditions, are present at birth, but may reveal signs and symptoms-including pain, bleeding, disfigurement, and functional defects of vital organs-in infancy, childhood, or adulthood. Vascular malformations often exhibit recurrent patterns at affected sites due to the lack of curative treatments. This review series provides a state-of-the-art assessment of vascular malformation research at basic, clinical, genetic, and translational levels.

Indexed as

Lymphatic AbnormalitiesVascular MalformationsAnimalsBlood VesselsGenetic Predisposition to DiseaseGenetic VariationHumansLymphatic VesselsPhenotypeRisk Factorsarteriescapillariescell proliferationhemangiomasvascular malformation

Identifiers

PMID34166069
PMCPMC8238353
OpenAlexW3175331742

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.