Evidence map›Paper›PMID 34165902›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021

Smart Cargo Delivery System based on Mesoporous Nanoparticles for Bone Disease Diagnosis and Treatment.

Panpan Pan, Qin Yue, Juan Li, Meiqi Gao, Xuanyu Yang, Yuan Ren, Xiaowei Cheng, Penglei Cui, Yonghui Deng

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 41 citations in OpenAlex.

  1. Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Biocompatible Mesoporous Materials for Bone Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Metabolic regulation by biomaterials in osteoblast.Frontiers in bioengineering and biotechnology · 2023
    Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Panpan PanDepartment of Chemistry, Department of Gastroenterology, Zhongshan Hospital of Fudan University, State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai, 200433, China.
Qin YueInstitute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China, Chengdu, 610051, China.
Juan LiDepartment of Chemistry, Department of Gastroenterology, Zhongshan Hospital of Fudan University, State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai, 200433, China.
Meiqi GaoDepartment of Chemistry, Department of Gastroenterology, Zhongshan Hospital of Fudan University, State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai, 200433, China.
Xuanyu YangDepartment of Chemistry, Department of Gastroenterology, Zhongshan Hospital of Fudan University, State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai, 200433, China.
Yuan RenDepartment of Chemistry, Department of Gastroenterology, Zhongshan Hospital of Fudan University, State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai, 200433, China.
Xiaowei ChengDepartment of Chemistry, Department of Gastroenterology, Zhongshan Hospital of Fudan University, State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai, 200433, China.
Penglei CuiDepartment of Orthopedic Surgery, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
Yonghui DengDepartment of Chemistry, Department of Gastroenterology, Zhongshan Hospital of Fudan University, State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai, 200433, China.ORCID 0000-0002-0657-9397
Fudan University · CNChinese Academy of Sciences · CNShanghai Jiao Tong University · CNUniversity of Electronic Science and Technology of China · CN

Funding

China Postdoctoral Science Foundation 2020M670973China Postdoctoral Science Foundation BX20200085National Key R&D Program of China 2020YFB2008600NSF 21875044NSF 22005057NSF 22005058NSF 52073064Program of Shanghai Academic Research Leader 19XD1420300state key laboratory of Transducer Technology of China SKT1904
6 · The paper itself

Abstract

Bone diseases constitute a major issue for modern societies as a consequence of progressive aging. Advantages such as open mesoporous channel, high specific surface area, ease of surface modification, and multifunctional integration are the driving forces for the application of mesoporous nanoparticles (MNs) in bone disease diagnosis and treatment. To achieve better therapeutic effects, it is necessary to understand the properties of MNs and cargo delivery mechanisms, which are the foundation and key in the design of MNs. The main types and characteristics of MNs for bone regeneration, such as mesoporous silica (mSiO

Indexed as

Bone DiseasesBone RegenerationDrug CarriersDrug Delivery SystemsHumansNanoparticlesTissue EngineeringDrug Carriersbone targetingdiagnosis and treatmentmesoporous nanoparticlesmart cargo deliverystimuli responsiveness

Identifiers

PMID34165902
PMCPMC8224433
OpenAlexW3139126412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.