ArticleThe international journal of cardiovascular imaging2021
The prognostic value of right ventricular longitudinal strain and 3D ejection fraction in patients with dilated cardiomyopathy.
Article in The international journal of cardiovascular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The prognostic value of right ventricular longitudinal strain in heart failure: a systematic review and meta-analysis.Heart failure reviews · 2023Pooled it
- Pooled it
- Right Ventricular Systolic Dysfunction Predicts Recovery of Left Ventricular Systolic Function and Reduced Quality of Life in Patients With Arrhythmia-Induced Cardiomyopathy.Clinical cardiology · 2025Trial
- Prognostic Relevance of Speckle Tracking-Derived Biatrial Stiffness Index in Patients with Dilated Cardiomyopathy.Journal of clinical medicine · 2026Article
- Prognostic Value of Non-Invasively Determined Right Ventricular-Arterial Coupling Surrogate Parameters in Patients with Dilated Cardiomyopathy.Journal of clinical medicine · 2026Article
- Prognostic value of right ventricular ejection fraction using three-dimensional echocardiography in patients with ischemic and dilated cardiomyopathy.Journal of echocardiography · 2026Article
- Advancements and challenges in pediatric dilated cardiomyopathy: a comprehensive review of current approaches and future directions.European journal of pediatrics · 2025Review
- Refining Prognostication and Therapeutic Guidance Through Advances in Right Heart Imaging Approaches.The Canadian journal of cardiology · 2025Review
- Right Ventricular Strain by Echocardiography: Current Clinical Applications and Future Directions for Mechanics Assessment of the Forgotten Ventricle.Journal of personalized medicine · 2025Review
- Echocardiographic Updates in the Assessment of Cardiomyopathy.Current cardiology reports · 2025Review
- Preoperative right ventricular strain as an early predictor of perioperative cardiac failure in patients undergoing mitral surgery: An exploratory study.Health science reports · 2024Article
- Perioperative echocardiographic strain analysis: what anesthesiologists should know.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024Review
- The Added Value of Advanced Echocardiography for the Morpho-Functional and Prognostic Evaluation of the Right Heart in Dilated Cardiomyopathy: Do Not Forget about the Right Atrium.Journal of clinical medicine · 2024Article
- Speckle tracking echocardiography for diagnosis of right ventricular failure in children with totally corrected tetralogy of Fallot in Sulaimani, Iraq.Journal of Taibah University Medical Sciences · 2024Article
- Three-Dimensional Combined Atrioventricular Coupling Index-A Novel Prognostic Marker in Dilated Cardiomyopathy.Biomedicines · 2024Article
- Echocardiography Imaging of the Right Ventricle: Focus on Three-Dimensional Echocardiography.Diagnostics (Basel, Switzerland) · 2023Review
- Dilated Cardiomyopathy: A Comprehensive Approach to Diagnosis and Risk Stratification.Biomedicines · 2023Review
- Added value of 3D echocardiography in the diagnosis and prognostication of patients with right ventricular dysfunction.Frontiers in cardiovascular medicine · 2023Review
- Article
- The Dysfunctional Right Ventricle in Dilated Cardiomyopathies: Looking from the Right Point of View.Journal of cardiovascular development and disease · 2022Review
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several studies showed that right ventricular (RV) dysfunction is a powerful predictor in heart failure (HF). Advanced echocardiographic techniques such as speckle-tracking imaging and three-dimensional (3D) echocardiography proved to be accurate tools for RV assessment, but their clinical significance remains to be clarified. The aim of this study was to evaluate the role of two-dimensional (2D) RV strain and 3D ejection fraction (RVEF) in predicting adverse outcome in patients with non-ischemic dilated cardiomyopathy (DCM). We prospectively screened 81 patients with DCM and sinus rhythm, 50 of whom were enrolled and underwent comprehensive echocardiography, including RV strain and 3D RV volumetric assessment. Patients were followed for a composite endpoint of cardiac death, nonfatal cardiac arrest and acute worsening of HF requiring hospitalization. After a median follow-up of 16 months, 29 patients reached the primary endpoint. Patients with events had more impaired RV global longitudinal strain (- 10.5 ± 4.5% vs. - 14.3 ± 5.2%, p = 0.009), RV free wall longitudinal strain (- 12.9 ± 8.7% vs. - 17.5 ± 7.1%, p = 0.046) and 3D RVEF (38 ± 8% vs. 47 ± 9%, p = 0.001). By Cox proportional hazards multivariable analysis, RV global longitudinal strain and RVEF were independent predictors of outcome after adjustment for age and NYHA class. RVEF remained the only independent predictor of events after further correction for echocardiographic risk factors. By receiver-operating characteristic analysis, the optimal RVEF cut-off value for event prediction was 43.4% (area under the curve = 0.768, p = 0.001). Subjects with RVEF > 43.4% showed more favourable outcome compared to those with RVEF < 43.4% (log-rank test, p < 0.001). In conclusion, 3D RVEF is an independent predictor of major adverse cardiovascular events in patients with DCM.
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