Evidence map›Paper›PMID 34165686›Full record

ArticleJournal of chemical ecology2021

BoaγPLI from Boa constrictor Blood is a Broad-Spectrum Inhibitor of Venom PLA

Caroline Fabri Bittencourt Rodrigues, Christina N Zdenek, Caroline Serino-Silva, Karen de Morais-Zani, Kathleen Fernandes Grego, Melisa Bénard-Valle, Edgar Neri-Castro, Alejandro Alagón, Anita Mitico Tanaka-Azevedo, Bryan Grieg Fry

Abstract read
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In one paragraph

Article in Journal of chemical ecology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Convergent evolution of toxin resistance in animals.Biological reviews of the Cambridge Philosophical Society · 2022
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Caroline Fabri Bittencourt RodriguesVenom Evolution Lab, School of Biological Sciences, The University of Queensland, St. Lucia, QLD, 4072, Australia.
Christina N ZdenekVenom Evolution Lab, School of Biological Sciences, The University of Queensland, St. Lucia, QLD, 4072, Australia.
Caroline Serino-SilvaLaboratório de Herpetologia, Instituto Butantan, São Paulo, Brazil.
Karen de Morais-ZaniLaboratório de Herpetologia, Instituto Butantan, São Paulo, Brazil.
Kathleen Fernandes GregoLaboratório de Herpetologia, Instituto Butantan, São Paulo, Brazil.
Melisa Bénard-ValleInstituto de Biotecnología, Universidad Nacional Autónoma de México, Av. Universidad 2001, 62210, Cuernavaca, Morelos, Mexico.
Edgar Neri-CastroInstituto de Biotecnología, Universidad Nacional Autónoma de México, Av. Universidad 2001, 62210, Cuernavaca, Morelos, Mexico.
Alejandro AlagónInstituto de Biotecnología, Universidad Nacional Autónoma de México, Av. Universidad 2001, 62210, Cuernavaca, Morelos, Mexico.
Anita Mitico Tanaka-AzevedoLaboratório de Herpetologia, Instituto Butantan, São Paulo, Brazil.
Bryan Grieg FryVenom Evolution Lab, School of Biological Sciences, The University of Queensland, St. Lucia, QLD, 4072, Australia. bgfry@uq.edu.au.
Instituto Butantan · BRUniversidad Nacional Autónoma de México · MXUniversity of Queensland · AU

Funding

Australian Research Council DP190100304Fundação de Apoio à Pesquisa do Estado de São Paulo FAPESP 2018/25786-0
6 · The paper itself

Abstract

The use of venom in predation exerts a corresponding selection pressure for the evolution of venom resistance. One of the mechanisms related to venom resistance in animals (predators or prey of snakes) is the presence of molecules in the blood that can bind venom toxins, and inhibit their pharmacological effects. One such toxin type are venom phospholipase A

Indexed as

BoidaeCoral SnakesSympatryAnimalsPhospholipases A2Predatory BehaviorReptilian ProteinsSnake VenomsVenomsPhospholipases A2Reptilian ProteinsSnake VenomsVenomsAnticoagulationEndogenous inhibitorsPLA2 inhibitorVenom resistance

Identifiers

PMID34165686
OpenAlexW3173414933

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.