Evidence map›Paper›PMID 34165428›Full record

ArticleeLife2021

The Prop1-like homeobox gene

Emily G Berghoff, Lori Glenwinkel, Abhishek Bhattacharya, HaoSheng Sun, Erdem Varol, Nicki Mohammadi, Amelia Antone, Yi Feng, Ken Nguyen, Steven J Cook and 7 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
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  8. Article
  9. Nervous system-wide analysis of allScience advances · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Almost 40 years of studying homeobox genes in C. elegans.Development (Cambridge, England) · 2024
    Article
  14. Review
  15. Functional analysis of conservedbioRxiv : the preprint server for biology · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Emily G BerghoffDepartment of Biological Sciences, Columbia University, Howard Hughes Medical Institute, New York, United States.
Lori GlenwinkelDepartment of Biological Sciences, Columbia University, Howard Hughes Medical Institute, New York, United States.
Abhishek BhattacharyaDepartment of Biological Sciences, Columbia University, Howard Hughes Medical Institute, New York, United States.
HaoSheng SunDepartment of Biological Sciences, Columbia University, Howard Hughes Medical Institute, New York, United States.ORCID 0000-0003-3919-559X
Erdem VarolDepartment of Statistics, Zuckerman Institute, Columbia University, New York, United States.
Nicki MohammadiDepartment of Biological Sciences, Columbia University, Howard Hughes Medical Institute, New York, United States.
Amelia AntoneDepartment of Biological Sciences, Columbia University, Howard Hughes Medical Institute, New York, United States.
Yi FengDepartment of Biological Sciences, Columbia University, Howard Hughes Medical Institute, New York, United States.
Ken NguyenDominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, United States.
Steven J CookDepartment of Biological Sciences, Columbia University, Howard Hughes Medical Institute, New York, United States.ORCID 0000-0002-1345-7566
Jordan F WoodDepartment of Biological Sciences, University at Buffalo, The State University of New York, Buffalo, United States.
Neda MasoudiDepartment of Biological Sciences, Columbia University, Howard Hughes Medical Institute, New York, United States.
Cyril C CrosDepartment of Biological Sciences, Columbia University, Howard Hughes Medical Institute, New York, United States.
Yasmin H RamadanDepartment of Biological Sciences, Columbia University, Howard Hughes Medical Institute, New York, United States.
Denise M FerkeyDepartment of Biological Sciences, University at Buffalo, The State University of New York, Buffalo, United States.
David H HallDominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, United States.ORCID 0000-0001-8459-9820
Oliver HobertDepartment of Biological Sciences, Columbia University, Howard Hughes Medical Institute, New York, United States.ORCID 0000-0002-7634-2854
Howard Hughes Medical Institute · USAlbert Einstein College of Medicine · USUniversity at Buffalo, State University of New York · USColumbia University · US

Funding

Center for C elegans AnatomyR24OD010943 · OD · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI DAVID H. HALL, Nathan Schroeder · 2012 to 2026
$9.6M
CENTER FOR CAENORHABDITIS ELGANS ANATOMYR24RR012596 · NCRR · YESHIVA UNIVERSITY · PI HALL, DAVID H. · 1998 to 2011
$8.0M
SUPPORT FOR THE ROSE F KENNEDY IDDRC P50P50HD105352 · NICHD · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Julie Secombe · 2021 to 2026
$7.0M
The neuropeptidergic connectome of Caenorhabitis elegantR01NS110391 · NINDS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI BEETS, ISABEL, HOBERT, OLIVER · 2018 to 2021
$2.0M
Howard Hughes Medical InstituteNCRR NIH HHS R24 RR012596NICHD NIH HHS P50 HD105352NIH HHS 1R01NS110391NIH HHS OD010943NIH HHS R24 OD010943NINDS NIH HHS R01 NS110391
6 · The paper itself

Abstract

Many neuronal identity regulators are expressed in distinct populations of cells in the nervous system, but their function is often analyzed only in specific isolated cellular contexts, thereby potentially leaving overarching themes in gene function undiscovered. We show here that the

Indexed as

AnimalsBody PatterningCaenorhabditis elegansCaenorhabditis elegans ProteinsEmbryo, NonmammalianHomeodomain ProteinsInterneuronsMotor NeuronsSensory Receptor CellsSynapsesCaenorhabditis elegans ProteinsHomeodomain Proteinsunc-42 protein, C elegansC. elegansgeneticsneurosciencetranscription factor

Identifiers

PMID34165428
PMCPMC8225392
OpenAlexW3176762080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.