Evidence map›Paper›PMID 34165333›Full record

ArticleMicrobiology resource announcements2021

Complete Genome Sequence of Streptococcus mutans 27-3, an Active Extracellular Membrane Vesicle Producer.

Xiaochang Huang, Justin Merritt, Zezhang Tom Wen

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology resource announcements, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Xiaochang HuangDepartment of Oral and Craniofacial Biology, School of Dentistry, Louisiana State University Health, New Orleans, Louisiana, USA.
Justin MerrittDepartment of Restorative Dentistry, Oregon Health and Science University, Portland, Oregon, USA.
Zezhang Tom WenDepartment of Oral and Craniofacial Biology, School of Dentistry, Louisiana State University Health, New Orleans, Louisiana, USA.
Louisiana State University Health Sciences Center New Orleans · USOregon Health & Science University · US

Funding

Advancing studies of polymicrobial diseases via streptococcal geneticsR35DE028252 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI MERRITT, JUSTIN · 2018 to 2025
$7.8M
BrpA in Virulence Modulation of Streptococcus mutansR01DE019452 · NIDCR · LSU HEALTH SCIENCES CENTER · PI ZEZHANG TOM WEN, Hui Wu · 2009 to 2026
$6.3M
eDNA Secretion and eDNA-Cell Interactions in Biofilm FormationR21DE025348 · NIDCR · LSU HEALTH SCIENCES CENTER · PI BRADY, L. JEANNINE, WEN, ZEZHANG TOM · 2016 to 2017
$419k
HHS | National Institutes of Health (NIH) DE19452NIDCR NIH HHS R01 DE019452NIDCR NIH HHS R21 DE025348NIDCR NIH HHS R35 DE028252
6 · The paper itself

Abstract

Here, we report the complete genome sequence of Streptococcus mutans 27-3. Isolated from a caries-active patient, 27-3 produces significantly more extracellular membrane vesicles than the commonly used laboratory strain UA159. This study provides useful information for comparative genomic analysis and better understanding of regulation of vesiculogenesis in this bacterium.

Identifiers

PMID34165333
PMCPMC8223807
OpenAlexW3177275952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.