Evidence map›Paper›PMID 34165256›Full record

ArticleCancer reports (Hoboken, N.J.)2022

Patient-reported symptom burden in routine oncology care: Examining racial and ethnic disparities.

Hailey W Bulls, Pi-Hua Chang, Naomi C Brownstein, Jun-Min Zhou, Aasha I Hoogland, Brian D Gonzalez, Peter Johnstone, Heather S L Jim

Open access · goldAbstract read
In one paragraph

Article in Cancer reports (Hoboken, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Management of Fatigue in Adult Survivors of Cancer: ASCO-Society for Integrative Oncology Guideline Update.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Guideline
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Shared decision making in routine oncology appointments with Black patients with lung cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Observational
  10. Article
  11. Review
  12. Article
  13. Article
  14. An initiative to implement a triage and referral system to make exercise and rehabilitation referrals standard of care in oncology.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  15. Article
  16. Acute cancer-related symptoms and concerns among patients receiving chemotherapy: current state of the science.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Observational
  17. Article
  18. Race Differences in Patient-Reported Symptoms during Chemotherapy among Women with Early-Stage Hormone Receptor-Positive Breast Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Observational
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Hailey W BullsDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, Florida, USA.ORCID 0000-0003-1005-0303
Pi-Hua ChangDepartment of Nursing, Taichung Veterans General Hospital, Taichung, Taiwan, ROC.
Naomi C BrownsteinDepartment of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, Florida, USA.ORCID 0000-0002-9991-427X
Jun-Min ZhouDepartment of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, Florida, USA.
Aasha I HooglandDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, Florida, USA.ORCID 0000-0002-8691-8132
Brian D GonzalezDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, Florida, USA.
Peter JohnstoneDepartment of Radiation Oncology, Moffitt Cancer Center, Tampa, Florida, USA.
Heather S L JimDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, Florida, USA.ORCID 0000-0001-7353-3711
Moffitt Cancer Center · USNational Taiwan University · TWUniversity of Pittsburgh · US

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI Christine O'Connell · 1998 to 2026
$93.5M
Behavioral Oncology Education & Career DevelopmentR25CA090314 · NCI · H. LEE MOFFITT CANCER CTR &RES INST · PI BRANDON, THOMAS H · 2003 to 2018
$4.0M
Improving Prediction of Chemotherapy-Induced Nausea: Integrating Genes, Behavior, and the MicrobiomeR01CA219389 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI JIM, HEATHER S.L. · 2018 to 2022
$3.5M
Randomized Placebo Controlled Trial of Bupropion for Cancer Related FatigueR01CA214647 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI JIM, HEATHER S.L. · 2018 to 2022
$3.0M
Behavioral Oncology Education & Career DevelopmentT32CA090314 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI Vani N Simmons, SUSAN T VADAPARAMPIL · 2019 to 2026
$2.9M
Developing a Culturally Targeted mHealth Intervention for Cancer-Related Sleep Disturbance in African American Breast Cancer SurvivorsK01CA211789 · NCI · RBHS -CANCER INSTITUTE OF NEW JERSEY · PI GONZALEZ, BRIAN D · 2016 to 2019
$585k
NCI NIH HHS K01 CA211789NCI NIH HHS P30 CA076292NCI NIH HHS R01 CA214647NCI NIH HHS R01 CA219389NCI NIH HHS R25 CA090314NCI NIH HHS T32 CA090314Taichung Veterans General Hospital and Veterans Affairs Council 2018Y-77
6 · The paper itself

Abstract

backgroundRacial and ethnic disparities are well-documented in cancer outcomes such as disease progression and survival, but less is known regarding potential disparities in symptom burden.

aimsThe goal of this retrospective study was to examine differences in symptom burden by race and ethnicity in a large sample of cancer patients. We hypothesized that racial and ethnic minority patients would report greater symptom burden than non-Hispanic and White patients. METHODS AND

resultsA total of 5798 cancer patients completed the Edmonton Symptom Assessment Scale-revised (ESAS-r-CSS) at least once as part of clinical care. Two indicators of symptom burden were evaluated: (1) total ESAS-r-CSS score (i.e., overall symptom burden) and (2) number of severe symptoms (i.e., severe symptomatology). For patients completing the ESAS-r-CSS on multiple occasions, the highest score for each indicator was used. Zero-inflated negative binomial regression analyses were conducted, adjusting for other sociodemographic and clinical characteristics. Symptomology varied across race. Patients who self-identified as Black reported higher symptom burden (p = .016) and were more likely to report severe symptoms (p < .001) than self-identified White patients. Patients with "other" race were also more likely to report severe symptoms than White patients (p = .032), but reported similar total symptom burden (p = .315). Asian and Hispanic patients did not differ from White or non-Hispanic patients on symptom burden (ps > .05).

conclusionThis study describes racial disparities in patient-reported symptom burden during routine oncology care, primarily observed in Black patients. Clinic-based electronic symptom monitoring may be useful to detect high symptom burden, particularly in patients who self-identify their race as Black or other. Future research is needed to reduce symptom burden in racially diverse cancer populations.

Indexed as

EthnicityMinority GroupsBlack PeopleHumansPatient Reported Outcome MeasuresRetrospective Studiesent-reported outcomesracial disparitiessymptom assessmentethnic disparitiesoncologypati

Identifiers

PMID34165256
PMCPMC8955049
OpenAlexW3174132700

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.