Evidence map›Paper›PMID 34165251›Full record

ReviewNursing open2022

Treating the most vulnerable: A discursive review of experimental pain in Alzheimer's disease.

Wm Larkin Iversen, Ronald L Cowan, Sebastian Atalla, Sydney S Englehart, Tanya R Gure, Karen O Moss, Claire M Ryan, Douglas W Scharre, Kathy D Wright, Todd B Monroe

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nursing open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Wm Larkin IversenThe Ohio State University College of Nursing, The Ohio State University, Columbus, OH, USA.ORCID 0000-0001-8666-9511
Ronald L CowanDepartment of Psychiatry, The University of Tennessee Health Science Center, Memphis, TN, USA.
Sebastian AtallaThe Ohio State University College of Nursing, The Ohio State University, Columbus, OH, USA.
Sydney S EnglehartThe Ohio State University College of Nursing, The Ohio State University, Columbus, OH, USA.
Tanya R GureDivision of General Internal Medicine and Geriatrics, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
Karen O MossThe Ohio State University College of Nursing, The Ohio State University, Columbus, OH, USA.
Claire M RyanVanderbilt Department of Psychiatry and Behavioral Sciences, Nashville, TN, USA.
Douglas W ScharreDepartment of Neurology, Division of Cognitive Neurology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.ORCID 0000-0001-8622-3923
Kathy D WrightThe Ohio State University College of Nursing, The Ohio State University, Columbus, OH, USA.
Todd B MonroeThe Ohio State University College of Nursing, The Ohio State University, Columbus, OH, USA.
The Ohio State University · USThe Ohio State University Wexner Medical Center · USUniversity of Tennessee Health Science Center · USVanderbilt University · US

Funding

Pain Sensitivity and Unpleasantness in People with Alzheimer's Disease and CancerR01AG061325 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI COWAN, RONALD L, MONROE, TODD BRYANT · 2019 to 2023
$4.7M
Sex Differences in Pain Reports and Brain Activation in Older Adults with Alzheimers DiseaseR01AG059861 · NIA · OHIO STATE UNIVERSITY · PI MONROE, TODD BRYANT · 2018 to 2022
$3.6M
Brain Activation and Pain Reports in People with Alzheimer's DiseaseK23AG046379 · NIA · VANDERBILT UNIVERSITY · PI MONROE, TODD BRYANT · 2015 to 2018
$627k
NIA NIH HHS K23 AG046379NIA NIH HHS R01 AG059861NIA NIH HHS R01 AG061325
6 · The paper itself

Abstract

aimThe purpose of this manuscript is to summarize research on how experimental pain is experienced by adults with Alzheimer's disease (AD) and to translate results into implications for nurses.

designThis discursive review synthesizes the results of three previous research studies exploring experimental pain in adults with AD.

methodsUsing a series of fictional clinical vignettes, the authors discuss how the results from three previous papers using acute experimental pain can potentially be translated into clinical practice. The authors also introduce the reader to the concept of research-related psychophysics using introductory definitions and concepts with the impetus to encourage other nurses to consider this research methodology.

resultsPain characteristics in AD that differ from cognitively intact controls must be explored to properly address pain in this population. Nurses are well positioned to address these issues in order to provide a high quality of care to adults with AD.

Indexed as

Alzheimer DiseaseHumansPainPain MeasurementPsychophysicsdementiapainpsychophysics

Identifiers

PMID34165251
PMCPMC8859087
OpenAlexW3175011643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.