Evidence map›Paper›PMID 34164967›Full record

ArticleJournal of biomedical optics2021

Mobile-based oral cancer classification for point-of-care screening.

Bofan Song, Sumsum Sunny, Shaobai Li, Keerthi Gurushanth, Pramila Mendonca, Nirza Mukhia, Sanjana Patrick, Shubha Gurudath, Subhashini Raghavan, Tsusennaro Imchen and 13 more

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  13. Revolutionizing Oral Cancer Screening: New Approaches and Emerging Technologies.Asian Pacific journal of cancer prevention : APJCP · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Bofan SongWyant College of Optical Sciences, The Univ. of Arizona, United States.
Sumsum SunnyMazumdar Shaw Medical Ctr., India.
Shaobai LiWyant College of Optical Sciences, The Univ. of Arizona, United States.
Keerthi GurushanthKLE Society's Institute of Dental Sciences, India.
Pramila MendoncaMazumdar Shaw Medical Foundation, India.
Nirza MukhiaK.L.E. Society's Institute of Dental Sciences, India.
Sanjana PatrickBiocon, India.
Shubha GurudathK.L.E. Society's Institute of Dental Sciences, India.
Subhashini RaghavanK.L.E. Society's Institute of Dental Sciences, India.
Tsusennaro ImchenChristian Institute of Health Sciences and Research, India.
Shirley LeivonChristian Institute of Health Sciences and Research, India.
Trupti KolurMazumdar Shaw Medical Foundation, India.
Vivek ShettyMazumdar Shaw Medical Foundation, India.
Vidya BushanMazumdar Shaw Medical Foundation, India.
Rohan RameshChristian Institute of Health Sciences & Research, India.
Natzem LimaWyant College of Optical Sciences, The Univ. of Arizona, United States.
Vijay PillaiMazumdar Shaw Medical Foundation, India.
Petra Wilder-SmithBeckman Laser Institute and Medical Clinic, Univ. of California, Irvine, United States.
Alben SigamaniMazumdar Shaw Medical Foundation, India.
Amritha SureshMazumdar Shaw Medical Ctr., India.
Moni KuriakoseMazumdar Shaw Medical Ctr., India.
Praveen BirurK.L.E. Society's Institute of Dental Sciences, India.
Rongguang LiangWyant College of Optical Sciences, The Univ. of Arizona, United States.

Funding

Multimodal Intraoral Imaging System for Oral Cancer Detection and Diagnosis in Low Resource SettingR01DE030682 · NIDCR · UNIVERSITY OF ARIZONA · PI LIANG, RONGGUANG · 2021 to 2025
$2.8M
Low-cost Mobile Oral Cancer Screening for Low Resource SettingUH3CA239682 · NCI · UNIVERSITY OF ARIZONA · PI LIANG, RONGGUANG · 2018 to 2020
$2.5M
Low-cost Mobile Oral Cancer Screening for Low Resource SettingUH2EB022623 · NIBIB · UNIVERSITY OF ARIZONA · PI LIANG, RONGGUANG · 2016 to 2017
$996k
NCI NIH HHS UH3 CA239682NIBIB NIH HHS UH2 EB022623NIDCR NIH HHS R01 DE030682
6 · The paper itself

Abstract

significanceOral cancer is among the most common cancers globally, especially in low- and middle-income countries. Early detection is the most effective way to reduce the mortality rate. Deep learning-based cancer image classification models usually need to be hosted on a computing server. However, internet connection is unreliable for screening in low-resource settings.

aimTo develop a mobile-based dual-mode image classification method and customized Android application for point-of-care oral cancer detection. APPROACH: The dataset used in our study was captured among 5025 patients with our customized dual-modality mobile oral screening devices. We trained an efficient network MobileNet with focal loss and converted the model into TensorFlow Lite format. The finalized lite format model is ∼16.3  MB and ideal for smartphone platform operation. We have developed an Android smartphone application in an easy-to-use format that implements the mobile-based dual-modality image classification approach to distinguish oral potentially malignant and malignant images from normal/benign images.

resultsWe investigated the accuracy and running speed on a cost-effective smartphone computing platform. It takes ∼300  ms to process one image pair with the Moto G5 Android smartphone. We tested the proposed method on a standalone dataset and achieved 81% accuracy for distinguishing normal/benign lesions from clinically suspicious lesions, using a gold standard of clinical impression based on the review of images by oral specialists.

conclusionsOur study demonstrates the effectiveness of a mobile-based approach for oral cancer screening in low-resource settings.

Indexed as

Mouth NeoplasmsPoint-of-Care SystemsEarly Detection of CancerHumansSensitivity and SpecificitySmartphonedual-modalityefficient deep learningmobile screening deviceoral cancer

Identifiers

PMID34164967
PMCPMC8220969

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.