Evidence map›Paper›PMID 34164950›Full record

ReviewCancer reports (Hoboken, N.J.)2022

High-dose-rate brachytherapy for prostate cancer: Rationale, current applications, and clinical outcome.

Iosif Strouthos, Efstratios Karagiannis, Nikolaos Zamboglou, Konstantinos Ferentinos

Abstract readReview
In one paragraph

Review in Cancer reports (Hoboken, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Influence of demographic change on the demand for radiotherapy using forecasted predictions for prostate cancer in Germany.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2024
    Article
  8. Article
  9. PersonalisedFrontiers in physiology · 2024
    Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Iosif StrouthosDepartment of Radiation Oncology, German Oncology Center, Limassol, Cyprus.ORCID 0000-0001-6229-5471
Efstratios KaragiannisDepartment of Radiation Oncology, German Oncology Center, Limassol, Cyprus.
Nikolaos ZamboglouDepartment of Radiation Oncology, German Oncology Center, Limassol, Cyprus.
Konstantinos FerentinosDepartment of Radiation Oncology, German Oncology Center, Limassol, Cyprus.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh-dose-rate brachytherapy (HDR BRT) has been enjoying rapid acceptance as a treatment modality offered to selected prostate cancer patients devoid of risk group, employed either in monotherapy setting or combined with external beam radiation therapy (EBRT) and is currently one of the most active clinical research areas. RECENT

findingsThis review encompasses all the current evidence to support the use of HDR BRT in various clinical scenario and shines light to the HDR BRT rationale, as an ultimately conformal dose delivery method enabling safe dose escalation to the prostate.

conclusionValid long-term data, both in regard to the oncologic outcomes and toxicity profile, support the current clinical indication spectrum of HDR BRT. At the same time, this serves as solid, rigid ground for emerging therapeutic applications, allowing the technique to remain in the spotlight alongside stereotactic radiosurgery.

Indexed as

BrachytherapyDose Fractionation, RadiationHumansMaleProstatic Neoplasmscombined with EBRThigh-dose-rateinterstitial brachytherapymonotherapyprostate cancersalvage

Identifiers

PMID34164950
PMCPMC8789612

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.