SynthesisJournal of the International AIDS Society2021
Mental health interventions for persons living with HIV in low- and middle-income countries: a systematic review.
Synthesis in Journal of the International AIDS Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Community-based mental health and well-being interventions for older adults in low- and middle-income countries: a systematic review and meta-analysis.BMC geriatrics · 2022Pooled it
- Impacts of psychological wellbeing with HIV/AIDS and cancer among sexual and gender minorities: A systematic review and meta-analysis.Frontiers in public health · 2022Pooled it
- Mental health interventions for persons living with HIV in low- and middle-income countries: a systematic review.Journal of the International AIDS Society · 2021Pooled it
- Acceptability of an Integrated Model of Mental Health and PrEP Service Delivery for South African Adolescent Girls: Qualitative Results from a Pilot Hybrid Effectiveness-Implementation Randomized Trial.AIDS and behavior · 2026Trial
- Increased prevalence of depression and anxiety among adults initiating antiretroviral therapy during the COVID-19 pandemic in Shinyanga region, Tanzania.AIDS research and therapy · 2023Trial
- Long-Term Effect of Group Support Psychotherapy on Depression and HIV Treatment Outcomes: Secondary Analysis of a Cluster Randomized Trial in Uganda.Psychosomatic medicine · 2022Trial
- Long-term Effects of a Social Media-Based Intervention (Run4Love) on Depressive Symptoms of People Living With HIV: 3-Year Follow-up of a Randomized Controlled Trial.Journal of medical Internet research · 2022Trial
- Economic Empowerment Interventions on Mental Health Outcomes Among People Living with HIV in Low and Middle-Income Countries: A Systematic Literature Review.Behavioral sciences (Basel, Switzerland) · 2026Review
- Service capacity of institutions serving the mental health needs of persons living with HIV in Georgia.AIDS care · 2026Article
- A qualitative study to explore barriers to access behavioral health services among older people living with HIV in Georgia.AIDS care · 2026Article
- Article
- The effectiveness of cognitive behavioral therapy-based interventions for depression and anxiety in people living with HIV in low- and middle-income countries: A systematic review and meta-analysis.Global mental health (Cambridge, England) · 2026Article
- Determinants associated with non-adherence to antiretroviral therapy (ART) and viral load suppression in PLHIV in Meta, Colombia.Journal of public health (Oxford, England) · 2025Article
- Experienced and anticipated HIV-related stigma and depression among pregnant and postpartum women living with HIV in the Greater Accra Region of Ghana: the role of internalized HIV stigma.BMC public health · 2025Article
- Counselling and depressive symptoms in older adults with HIV/AIDS in mbarara, Uganda.BMC psychology · 2025Article
- Prevalence and Determinants of Viral Suppression in Young People Living with HIV on Antiretroviral Therapy in Southern Africa: A Cross-Sectional Analysis of HIV Survey Data of 2020 and 2021.AIDS and behavior · 2025Article
- Mental Health Interventions for Young People Living With HIV/AIDS in Sub-Saharan Africa: A Systematic Review.AIDS research and treatment · 2025Review
- Implementation of group interpersonal therapy to treat depression in people living with HIV: A first evaluation of IPT dissemination in Senegal.Global mental health (Cambridge, England) · 2025Article
- Depression and the revolving door of HIV care: using multistate approaches to understand complex longitudinal exposure/outcome relationships among a cohort of people entering HIV care in Cameroon from 2019 to 2020.BMJ public health · 2025Article
- Face-to-face, confidential and health worker-led: Understanding the preferences for behavioral health services among people with HIV in Lesotho.Global mental health (Cambridge, England) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAddressing the intersection between mental health and HIV is critical for the wellbeing of persons living with HIV (PLWH). This systematic review synthesized the literature on mental health interventions for PLWH in low- and middle-income countries (LMICs) to determine intervention components and explore their relationship with intervention effectiveness.
methodsWe included only controlled clinical trials of interventions aiming to improve the mental health of PLWH. We conducted a search in the following databases: PubMed, CINAHL, PsycINFO and EMBASE for eligible studies describing the evaluation of interventions for mental health problems among PLWH in LMICs published through August 2020. Two reviewers independently screened references in two successive stages of title/abstract screening and then full-text screening for references meeting title/abstract criteria.
resultsWe identified a total of 30 eligible articles representing 6477 PLWH who were assigned to either the intervention arm (n = 3182) or control arm (n = 3346). The mental health interventions evaluated were psychological (n = 17, 56.67%), pharmacological (n = 6, 20.00%), combined psychological and pharmacological (n = 1, 3.33%) and complementary/alternative treatments (n = 6, 20.00%). The mental health problems targeted were depression (n = 22, 73.33 %), multiple psychological symptoms (n = 1, 3.33%), alcohol and substance use problems (n = 4, 13.33%), post-traumatic stress disorder (n = 1, 3.33%) and HIV-related neuro-cognitive impairment (n = 2, 6.67%). Studies of interventions with significant effects had significantly a higher number of active ingredients than those without significant effects [3.41 (2.24) vs. 1.84 (1.46) Mean (SD)] [Mean difference = -1.56, 95% CI = -3.03 to -0.09, p = 0.037].
conclusionsThere continue to be advances in mental health interventions for PLWH with mental illness in LMICs. However, more research is needed to elucidate how intervention components lead to intervention effectiveness. We recommend scale up of culturally appropriate interventions that have been successfully evaluated in low- and middle-income countries.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.