ArticleJA clinical reports2021
General anesthesia with remimazolam in a patient with mitochondrial encephalomyopathy: a case report.
Article in JA clinical reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Reply to Commentary: Finsterer, J. Outcome of General Anesthesia With Remimazolam in a m.3243A>G Carrier. Anesthesia Progress. 2026;73(1):51. doi: 10.2344/25-0017.Anesthesia progress · 2026Article
- Remimazolam-based anesthesia with intraoperative motor evoked potential monitoring in a patient with Leigh syndrome undergoing scoliosis surgery: a case report.JA clinical reports · 2026Article
- Perioperative Care of a Child With Combined Oxidative Phosphorylation Deficiency 6: Total Intravenous Anesthesia With Remimazolam.Journal of medical cases · 2025Article
- Single-Agent Total Intravenous Anesthesia With Remimazolam for an Elderly Man Undergoing Ambulatory Oral Surgery: A Case Report.Anesthesia progress · 2025Article
- Ischemic Stroke After Cochlear Implantation in a Patient With an Undiagnosed Mitochondrial Disorder.Cureus · 2025Article
- Anesthetic Management With Remimazolam for Adolescent Mitochondrial Encephalomyopathy With Lactic Acidosis and Stroke-like Episodes (MELAS): A Case Report.Anesthesia progress · 2025Article
- Safety of Remimazolam in Vulnerable Populations.Drug design, development and therapy · 2025Review
- Effective concentration of remifentanil for successful i-gel insertion during remimazolam induction.Korean journal of anesthesiology · 2023Article
- General anesthesia with remimazolam for a pediatric patient with MELAS and recurrent epilepsy: a case report.JA clinical reports · 2022Article
- Profile of Remimazolam in Anesthesiology: A Narrative Review of Clinical Research Progress.Drug design, development and therapy · 2022Review
- Remimazolam: An Updated Review of a New Sedative and Anaesthetic.Drug design, development and therapy · 2022Review
- Remimazolam: Non-Clinical and Clinical Profile of a New Sedative/Anesthetic Agent.Frontiers in pharmacology · 2021Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSystemic anesthetic management of patients with mitochondrial disease requires careful preoperative preparation to administer adequate anesthesia and address potential disease-related complications. The appropriate general anesthetic agents to use in these patients remain controversial. CASE PRESENTATION: A 54-year-old woman (height, 145 cm; weight, 43 kg) diagnosed with mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes underwent elective cochlear implantation. Infusions of intravenous remimazolam and remifentanil guided by patient state index monitoring were used for anesthesia induction and maintenance. Neither lactic acidosis nor prolonged muscle relaxation occurred in the perioperative period. At the end of surgery, flumazenil was administered to antagonize sedation, which rapidly resulted in consciousness.
conclusionsRemimazolam administration and reversal with flumazenil were successfully used for general anesthesia in a patient with mitochondrial disease.
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