ArticlePhysical review research2019
Elementwise approach for simulating transcranial MRI-guided focused ultrasound thermal ablation.
Article in Physical review research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- Stochastic numerical head phantoms to enable virtual imaging studies of transcranial photoacoustic computed tomography.Photoacoustics · 2026Article
- From Skull Density Ratio-based eligibility to efficiency-informed planning: Predictive modeling of thermal response in MR-guided focused ultrasound.Medical physics · 2026Article
- AN IN SILICO STUDY OF LOW-INTENSITY FOCUSED ULTRASOUND DISPLACEMENT MAPPING WITH A 220 KHZ CLINICAL PHASED-ARRAY TRANSDUCER.Proceedings. IEEE International Symposium on Biomedical Imaging · 2026Article
- Focused Ultrasound for the Treatment of Circuit and Molecular Pathology in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2026Review
- Numerical Validation of mSOUND Using Fully Heterogeneous Skull Models.IEEE open journal of ultrasonics, ferroelectrics, and frequency control · 2026Article
- Article
- A figure of merit for transcranial ultrasound transmission based on coupled elastic-thermal analysis.Physics in medicine and biology · 2025Article
- Influence of bone microstructure on ultrasound loss through skull-mimicking digital phantoms.Medical physics · 2025Article
- A comparative study of experimental and simulated ultrasound beam propagation through cranial bones.Physics in medicine and biology · 2025Article
- Non-Invasive Blood-Brain Barrier Disruption Using Acoustic Holography With a Clinical Focused Ultrasound System.IEEE transactions on bio-medical engineering · 2024Article
- CMUT as a Transmitter for Microbubble-Assisted Blood-Brain Barrier Opening.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2024Article
- Cavitation monitoring, treatment strategy, and acoustic simulations of focused ultrasound blood-brain barrier disruption in patients with glioblastoma.Journal of controlled release : official journal of the Controlled Release Society · 2024Article
- The influence of bone model geometries on the determination of skull acoustic properties.International journal for numerical methods in biomedical engineering · 2023Article
- Influence of cerebrospinal fluid on power absorption during transcranial magnetic resonance-guided focused ultrasound treatment.Medical physics · 2023Article
- Generating Patient-Specific Acoustic Simulations for Transcranial Focused Ultrasound Procedures Based on Optical Tracking Information.IEEE open journal of ultrasonics, ferroelectrics, and frequency control · 2023Article
- Comparison between MR and CT imaging used to correct for skull-induced phase aberrations during transcranial focused ultrasound.Scientific reports · 2022Article
- A Comparative Feasibility Study for Transcranial Extracorporeal Shock Wave Therapy.Biomedicines · 2022Article
- Two-step aberration correction: application to transcranial histotripsy.Physics in medicine and biology · 2022Article
- Adaptive Ultrasound Focusing Through the Cranial Bone for Non-invasive Treatment of Brain Disorders.Advances in experimental medicine and biology · 2022Article
- Acoustic Attenuation: Multifrequency Measurement and Relationship to CT and MR Imaging.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
This work explored an elementwise approach to model transcranial MRI-guided focused ultrasound (TcMRgFUS) thermal ablation, a noninvasive approach to neurosurgery. Each element of the phased array transducer was simulated individually and could be simultaneously loaded into computer memory, allowing for rapid (~2.5 s) calculation of the pressure field for different phase offsets used for beam steering and aberration correction. We simulated the pressure distribution for 431 sonications in 32 patients, applied the phase and magnitude values used during treatment, and estimated the resulting temperature rise. We systematically varied the relationship between CT (computerized tomography)-derived skull density and the acoustic attenuation and sound speed to obtain the best agreement between the predictions and MR temperature imaging (MRTI). The optimization was validated with simulations of 396 sonications from 40 additional treatments. After optimization, the predicted and measured heating agreed well (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.