ArticleClinical parkinsonism & related disorders2020
Identifying incident Parkinson's disease using administrative diagnostic codes: a validation study.
Article in Clinical parkinsonism & related disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Case Definitions and Data Sources for NNCSS Parkinson Disease Surveillance: A Systematic Review.JAMA network open · 2026Pooled it
- Revisiting the Association Between Calcium Channel Blockers and Parkinson's Disease in the E3N Cohort.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- GLP-1 and Parkinson's Disease: A Comprehensive Review of Biology, Mechanisms and Efficacy.Cells · 2026Review
- Parkinson's Disease Patients Face Higher 90-Day Readmission, Reoperation, and Infection Risk Following Total Knee Arthroplasty.Arthroplasty today · 2026Article
- Incidence and spatial variation of Parkinson's disease in the Netherlands (2017-2022): a population-based study.The Lancet regional health. Europe · 2026Article
- Social Determinants of Health and Their Association With Parkinson's Disease Prevalence in US Adults: Insights From NHANES 2001-2020.Behavioural neurology · 2026Article
- Neurodegeneration onset with glucagon-like peptide-1 receptor agonists in people with type 2 diabetes: a real-world multinational cohort study.Cardiovascular diabetology · 2025Article
- Incidence, prevalence and mortality of Parkinson's disease in Greece.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Use of β-adrenoreceptor drugs and Parkinson's disease incidence in women from the French E3N cohort study.Journal of Parkinson's disease · 2025Article
- Education Research: Exploring the Impact of Standardized, Condition-Specific Note Templates on Quality Metrics and Efficiency in Multiple Resident Clinics.Neurology. Education · 2025Article
- Validation of Parkinson's Disease Ascertainment in the Veterans Administration Electronic Medical Record.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- The epidemiology of Parkinson's disease.Lancet (London, England) · 2024Review
- Lifelong Association of Disorders Related to Military Trauma with Subsequent Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2023Article
- An update on pathogenesis and clinical scenario for Parkinson's disease: diagnosis and treatment.3 Biotech · 2023Review
- Risk of hospitalization in synucleinopathies and impact of psychosis.Frontiers in aging neuroscience · 2023Article
- Early detection of Parkinson's disease through enriching the electronic health record using a biomedical knowledge graph.Frontiers in medicine · 2023Article
- Traumatic Brain Injury and Risk of Alzheimer's Disease and Related Dementias in the Population.Journal of Alzheimer's disease : JAD · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundAdministrative databases that capture diagnostic codes are increasingly being used worldwide for research because they can save time and reduce costs. However, assessing validity is necessary before defining diseases using only diagnostic codes in research applications.
objectiveOur objective was to assess the validity of using diagnostic codes to identify incident Parkinson's disease (PD) cases in Olmsted County, Minnesota using an established standard for comparison (1976-2005).
methodsCases were identified solely using computer programs applied to administrative diagnostic code indexes from the Rochester Epidemiology Project (REP). Two codes >30 days apart or one code on the death certificate constituted PD. The standard was a clinical diagnosis by movement disorders specialists based on medical record review. Validity was assessed using positive predictive value (PPV) and sensitivity. Numbers of incident cases and incidence rates were compared between the two ascertainment methods by sex.
resultsThe codes only method over-counted the number of incident PD cases by 73% (804 versus 464), and this over-counting generally increased with calendar year. Sensitivity was 80% (95% CI [76%, 84%]) and PPV was 46% (95% CI [34%, 50%]). Disease status misclassification accounted for two-thirds of falsely identified cases, where individuals were found to not have PD (43%) or even parkinsonism (23%) after medical record review. The codes only method also over-estimated the incidence rate time trend for men and women by approximately two-fold.
conclusionIn our context, using administrative diagnostic codes only to identify incident PD cases is not recommended unless more accurate algorithms are developed.
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