Evidence map›Paper›PMID 34164605›Full record

ArticleJNCI cancer spectrum2021

Screening for Depression in Younger Breast Cancer Survivors: Outcomes From Use of the 9-item Patient Health Questionnaire.

Patricia A Ganz, Julienne E Bower, Ann H Partridge, Antonio C Wolff, Elissa D Thorner, Hadine Joffe, Michael R Irwin, Laura Petersen, Catherine M Crespi

Open access · goldAbstract read
In one paragraph

Article in JNCI cancer spectrum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Observational
  5. Review
  6. Article
  7. Article
  8. Article
  9. Improving Depression Screening in Adult Patients With Cancer.Journal of the advanced practitioner in oncology · 2024
    Article
  10. Article
  11. Work Productivity Among Younger Breast Cancer Survivors: The Impact of Behavioral Interventions for Depression.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2024
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Patricia A GanzDepartment of Health Policy and Management, UCLA Fielding School of Public Health, Los Angeles, CA, USA.ORCID 0000-0002-1841-4143
Julienne E BowerUCLA Jonsson Comprehensive Cancer Center, Los Angeles, CA, USA.
Ann H PartridgeMedical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.ORCID 0000-0002-4722-4824
Antonio C WolffThe Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA.ORCID 0000-0003-3734-1063
Elissa D ThornerThe Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA.
Hadine JoffeConnors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-7035-8249
Michael R IrwinUCLA Jonsson Comprehensive Cancer Center, Los Angeles, CA, USA.ORCID 0000-0002-1502-8431
Laura PetersenUCLA Jonsson Comprehensive Cancer Center, Los Angeles, CA, USA.ORCID 0000-0002-4843-2692
Catherine M CrespiUCLA Jonsson Comprehensive Cancer Center, Los Angeles, CA, USA.ORCID 0000-0002-6150-2181
UCLA Jonsson Comprehensive Cancer CenterJohns Hopkins University · USBrigham and Women's Hospital · USDana-Farber Cancer Institute · USUCLA Health · USUniversity of California, Los Angeles · US

Funding

Women's CancersP30CA016042 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Samuel Wheeler French · 1985 to 2026
$134.5M
UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
A Phase III Randomized Trial Targeting Behavioral Symptoms in Younger Breast Cancer SurvivorsR01CA200977 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BOWER, JULIENNE E, GANZ, PATRICIA A. · 2016 to 2020
$3.2M
NCATS NIH HHS UL1 TR001881NCI NIH HHS P30 CA016042NCI NIH HHS R01 CA200977
6 · The paper itself

Abstract

Background: Major cancer organizations recommend depression screening in patients and survivors. The 9-item Patient Health Questionnaire (PHQ-9) is often suggested, with limited information about its use. Methods: Enrollment data collected from younger breast cancer survivors participating in a behavioral intervention trial were used to examine the relationship between PHQ-9 scores (range = 0-27), patient characteristics, and responses to standardized psychosocial assessment tools. Major depressive disorder criterion was met if responses to the first 2 PHQ-9 items (range = 0-6) were 3 or greater. The sample was categorized by total PHQ-9 scores: less than 5 (minimal depressive symptoms), 5-9 (mild to moderate depressive symptoms), and 10 or greater (moderate to severe depression). PHQ-9 category associations with medical, demographic, psychosocial, and behavioral characteristics were examined using analysis of variance for continuous variables and χ Results: A total of 231 women met the study prescreening eligibility criterion of mild depressive symptoms and enrolled in the study. On average, they were 45.2 years old and 2.6 years since diagnosis. At enrollment, 22.1% met the screening criterion for possible major depressive disorder; among those with PHQ-9 scores of 10 or greater, 58.3% met this criterion. Anxiety, fatigue, insomnia, and intrusive thoughts about cancer were frequent and were associated with depressive symptom severity (all Conclusions: Depressive symptoms in this selected sample of younger breast cancer survivors were independent of demographic characteristics or cancer treatment history, suggesting that depression screening is necessary to detect uncontrolled depressive symptoms.

Indexed as

Patient Health QuestionnaireAnalysis of VarianceAnxietyBreast NeoplasmsCancer SurvivorsChi-Square DistributionDepressionFatigueFemaleHumansMajor Depressive DisorderMiddle AgedSleep Initiation and Maintenance DisordersSymptom AssessmentThinking

Identifiers

PMID34164605
PMCPMC8216636
OpenAlexW3128840807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.