Evidence map›Paper›PMID 34164520›Full record

ArticleAnnals of translational medicine2021

Attenuating glucose metabolism by

Hui-Peng Wang, Wen-Jie Chen, Jia-Men Shen, Tao Ye, Hong-Wei Xie

Open access · diamondAbstract read
In one paragraph

Article in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Molecular insights and clinical implications for the tumor suppressor role of SCFBiochimica et biophysica acta. Reviews on cancer · 2024
    Review
  6. Review
  7. Review
  8. Article
  9. NOX Dependent ROS Generation and Cell Metabolism.International journal of molecular sciences · 2023
    Review
  10. Targeting HDAC6 to Overcome Autophagy-Promoted Anti-Cancer Drug Resistance.International journal of molecular sciences · 2022
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hui-Peng WangDepartment of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
Wen-Jie ChenDepartment of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
Jia-Men ShenDepartment of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
Tao YeDepartment of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
Hong-Wei XieDepartment of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundColorectal cancer (CRC), one of the most common malignancies worldwide, is associated with poor survival and has a high mortality rate. Taxol is a chemotherapeutic agent that has been clinically applied as a first-line drug against diverse cancers. Yet, development of drug resistance has become the major challenge for anti-cancer treatments. F-box and WD40 domain protein 7 (

methodsWe report that

resultsOverexpression of

conclusionsCollectively, this study uncovered that targeting the

Indexed as

Colorectal cancer (CRC)F-box and WD40 domain protein 7 (Fbxw7)NADPH oxidase 1 (Nox1)Taxol sensitivity

Identifiers

PMID34164520
PMCPMC8184419
OpenAlexW3163991838

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.