Evidence map›Paper›PMID 34164417›Full record

ReviewFrontiers in medicine2021

Hyperoxemia Is Associated With Mortality in Critically Ill Children.

Jonathan H Pelletier, Sriram Ramgopal, Christopher M Horvat

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Bench evidence, bedside uncertainty: hyperoxia, mechanical ventilation and lung injury.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jonathan H PelletierDivision of Pediatric Critical Care Medicine, Department of Critical Care Medicine, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, United States.
Sriram RamgopalDepartment of Pediatrics, Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Christopher M HorvatDivision of Pediatric Critical Care Medicine, Department of Critical Care Medicine, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, United States.
Children's Hospital of Pittsburgh · USLurie Children's Hospital · US

Funding

PEDIATRIC NEUROINTENSIVE CARE AND RESUSCITATION RESEARCHT32HD040686 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Robert S B Clark, PATRICK M KOCHANEK · 2000 to 2026
$7.1M
A Learning Health System Approach to Precision Sedation and Analgesia in Critically-Ill ChildrenK23HD099331 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HORVAT, CHRISTOPHER MICHAEL · 2020 to 2024
$810k
NICHD NIH HHS K23 HD099331NICHD NIH HHS T32 HD040686
6 · The paper itself

Abstract

Multiple studies among adults have suggested a non-linear relationship between arterial partial pressure of oxygen (PaO

Indexed as

critically ill childrenhyperoxaemiamortalityoxygenreview

Identifiers

PMID34164417
PMCPMC8215123
OpenAlexW3166297744

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.