ArticleChemical science2021
Spontaneous emergence of membrane-forming protoamphiphiles from a lipid-amino acid mixture under wet-dry cycles.
Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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Who cites it
19 citing papers in PubMed, 46 citations in OpenAlex.
- Hydroxy acid conjugation to lipids increases structural and hydrolytic stability.Nature communications · 2026Article
- Repetitive temperature cycles with DMSO sustain RNA replicating liposome compartments via fusion mediated content exchange.Communications biology · 2026Article
- Increasing the Compositional Heterogeneity of Single-Chain Amphiphile Membranes Supported by Coacervate Cores Alters Stability and Properties of the Hybrid Protocells.Langmuir : the ACS journal of surfaces and colloids · 2026Article
- Organocatalyzed bottom-up formation of protocells.Nature communications · 2026Article
- Prebiotic Peptide Synthesis: How Did Longest Peptide Appear?Journal of molecular evolution · 2025Review
- The astrochemical evolutionary traits of phospholipid membrane homochirality.Nature reviews. Chemistry · 2024Review
- Evidence of Heritability in Prebiotically Realistic Membrane-Bound Systems.Life (Basel, Switzerland) · 2024Article
- Distinguishing Biotic vs. Abiotic Origins of 'Bio'signatures: Clues from Messy Prebiotic Chemistry for Detection of Life in the Universe.Life (Basel, Switzerland) · 2023Article
- Periodic temperature changes drive the proliferation of self-replicating RNAs in vesicle populations.Nature communications · 2023Article
- Lipid and Lipidation in Membrane Fusion.The Journal of membrane biology · 2022Review
- Elucidating N-acyl amino acids as a model protoamphiphilic system.Communications chemistry · 2022Article
- Novel Apparatuses for Incorporating Natural Selection Processes into Origins-of-Life Experiments to Produce Adaptively Evolving Chemical Ecosystems.Life (Basel, Switzerland) · 2022Article
- Synthesis and Characterization of Amino Acid Decyl Esters as Early Membranes for the Origins of Life.Membranes · 2022Article
- Prebiotic Membranes and Micelles Do Not Inhibit Peptide Formation During Dehydration.Chembiochem : a European journal of chemical biology · 2022Article
- Influence of Metal Ions on Model Protoamphiphilic Vesicular Systems: Insights from Laboratory and Analogue Studies.Life (Basel, Switzerland) · 2021Article
- Self-reproducing catalytic micelles as nanoscopic protocell precursors.Nature reviews. Chemistry · 2021Review
- Does Stochasticity Favour Complexity in a Prebiotic Peptide-Micelle System?Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2021Article
- Plausible Emergence and Self Assembly of a Primitive Phospholipid from Reduced Phosphorus on the Primordial Earth.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2021Review
- Origin of Life on Mars: Suitability and Opportunities.Life (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dynamic interplay between peptide synthesis and membrane assembly would have been crucial for the emergence of protocells on the prebiotic Earth. However, the effect of membrane-forming amphiphiles on peptide synthesis, under prebiotically plausible conditions, remains relatively unexplored. Here we discern the effect of a phospholipid on peptide synthesis using a non-activated amino acid, under wet-dry cycles. We report two competing processes simultaneously forming peptides and
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.