Evidence map›Paper›PMID 34164027›Full record

ArticleChemical science2021

A pH-responsive ultrathin Cu-based nanoplatform for specific photothermal and chemodynamic synergistic therapy.

Tingting Hu, Liang Yan, Zhengdi Wang, Weicheng Shen, Ruizheng Liang, Dongpeng Yan, Min Wei

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Recent advances in copper homeostasis-involved tumor theranostics.Asian journal of pharmaceutical sciences · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Heterogeneous-Driven Glutathione Oxidation: Defining the Catalytic Role of Chalcopyrite Nanoparticles.The journal of physical chemistry. C, Nanomaterials and interfaces · 2023
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Recent Progress of Sub-Nanometric Materials in Photothermal Energy Conversion.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tingting HuState Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology Beijing 100029 P. R. China liangrz@mail.buct.edu.cn weimin@mail.buct.edu.cn.
Liang YanState Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology Beijing 100029 P. R. China liangrz@mail.buct.edu.cn weimin@mail.buct.edu.cn.
Zhengdi WangState Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology Beijing 100029 P. R. China liangrz@mail.buct.edu.cn weimin@mail.buct.edu.cn.
Weicheng ShenState Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology Beijing 100029 P. R. China liangrz@mail.buct.edu.cn weimin@mail.buct.edu.cn.
Ruizheng LiangState Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology Beijing 100029 P. R. China liangrz@mail.buct.edu.cn weimin@mail.buct.edu.cn.ORCID https://orcid.org/0000-0002-3930-9625
Dongpeng YanBeijing Key Laboratory of Energy Conversion and Storage Materials, College of Chemistry, Beijing Normal University Beijing 100875 P. R. China yandp@bnu.edu.cn.
Min WeiState Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology Beijing 100029 P. R. China liangrz@mail.buct.edu.cn weimin@mail.buct.edu.cn.ORCID https://orcid.org/0000-0001-5257-790X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noninvasive tumor therapy requires a new generation of bionanomaterials towards sensitive response to the unique tumor microenvironment to achieve accurate and effective treatment. Herein, we have developed a tumor therapy nanoplatform by immobilizing natural glucose oxidase (GOD) onto Cu-based layered double hydroxide (CuFe-LDH) nanosheets, which for the first time integrates acid-enhanced photothermal therapy (PTT), and pH-responsive and heat-facilitated chemodynamic therapy (CDT) simultaneously. As demonstrated by EXAFS and HRTEM, CuFe-LDH nanosheets possess a considerable number of defects caused by different acid conditions, resulting in a significantly acid-enhanced photothermal conversion efficiency (83.2% at pH 5.4

Identifiers

PMID34164027
PMCPMC8179329

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.