Evidence map›Paper›PMID 34163969›Full record

ArticleChemical science2020

Site-to-site peptide transport on a molecular platform using a small-molecule robotic arm.

Salma Kassem, Alan T L Lee, David A Leigh, Augustinas Markevicius, Daniel J Tetlow, Naoyuki Toriumi

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 14 citations in OpenAlex.

  1. Artificial Supramolecular Pumps Powered by Light.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Salma KassemDepartment of Chemistry, University of Manchester Oxford Road Manchester M13 9PL UK david.leigh@manchester.ac.uk.
Alan T L LeeDepartment of Chemistry, University of Manchester Oxford Road Manchester M13 9PL UK david.leigh@manchester.ac.uk.
David A LeighDepartment of Chemistry, University of Manchester Oxford Road Manchester M13 9PL UK david.leigh@manchester.ac.uk.ORCID https://orcid.org/0000-0002-1202-4507
Augustinas MarkeviciusDepartment of Chemistry, University of Manchester Oxford Road Manchester M13 9PL UK david.leigh@manchester.ac.uk.
Daniel J TetlowDepartment of Chemistry, University of Manchester Oxford Road Manchester M13 9PL UK david.leigh@manchester.ac.uk.ORCID https://orcid.org/0000-0001-6323-3483
Naoyuki ToriumiDepartment of Chemistry, University of Manchester Oxford Road Manchester M13 9PL UK david.leigh@manchester.ac.uk.ORCID https://orcid.org/0000-0001-5963-4735
University of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptides attached to a cysteine hydrazide 'transporter module' are transported selectively in either direction between two chemically similar sites on a molecular platform, enabled by the discovery of new operating methods for a molecular transporter that functions through ratcheting. Substrate repositioning is achieved using a small-molecule robotic arm controlled by a protonation-mediated rotary switch and attachment/release dynamic covalent chemistry. A polar solvent mixtures were found to favour

Identifiers

PMID34163969
PMCPMC8179245
OpenAlexW3113185272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.