Evidence map›Paper›PMID 34163949›Full record

ArticleChemical science2020

Purely organic light-harvesting phosphorescence energy transfer by β-cyclodextrin pseudorotaxane for mitochondria targeted imaging.

Fang-Fang Shen, Yong Chen, Xianyin Dai, Hao-Yang Zhang, Bing Zhang, Yaohua Liu, Yu Liu

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 99 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Fang-Fang ShenCollege of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University Tianjin 300071 P. R. China yuliu@nankai.edu.cn.ORCID https://orcid.org/0000-0003-1171-3017
Yong ChenCollege of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University Tianjin 300071 P. R. China yuliu@nankai.edu.cn.
Xianyin DaiCollege of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University Tianjin 300071 P. R. China yuliu@nankai.edu.cn.
Hao-Yang ZhangCollege of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University Tianjin 300071 P. R. China yuliu@nankai.edu.cn.
Bing ZhangCollege of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University Tianjin 300071 P. R. China yuliu@nankai.edu.cn.
Yaohua LiuCollege of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University Tianjin 300071 P. R. China yuliu@nankai.edu.cn.
Yu LiuCollege of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University Tianjin 300071 P. R. China yuliu@nankai.edu.cn.ORCID https://orcid.org/0000-0001-8723-1896
Nankai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new type of purely organic light-harvesting phosphorescence energy transfer (PET) supramolecular assembly is constructed from 4-(4-bromophenyl)-pyridine modified β-cyclodextrin (CD-PY) as a donor, cucurbit[8]uril (CB[8]) as a mediator, rhodamine B (RhB) as an acceptor, and adamantane modified hyaluronic acid (HA-ADA) as a cancer cell targeting agent. Interestingly, the complexation of free CD-PY, which has no RTP emission in aqueous solution, with CB[8] results in the formation of CD-PY@CB[8] pseudorotaxane with an RTP emission at 510 nm. Then the addition of RhB leads to an efficient light-harvesting PET process with highly efficient energy transfer and an ultrahigh antenna effect (36.42) between CD-PY@CB[8] pseudorotaxane and RhB. Importantly, CD-PY@CB[8]@RhB assembles with HA-ADA into nanoparticles with further enhanced delayed emission at 590 nm. The nanoparticles could be successfully used for mitochondria targeted imaging in A549 cancer cells. This aqueous-state PET based on a supramolecular assembly strategy has potential application in delayed fluorescence cell imaging.

Identifiers

PMID34163949
PMCPMC8179139
OpenAlexW3110969803

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.