ArticleChemical science2020
Mechanochemical activation of disulfide-based multifunctional polymers for theranostic drug release.
Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 105 citations in OpenAlex.
- Forces in mechanically interlocked materials.Chemical Society reviews · 2026Review
- Modeling Targeted Mechanochemistry in Polymeric Solids.Chemical reviews · 2026Review
- Mechanochemical disassembly pathways of self-assembled polymer-decorated PdNature communications · 2026Article
- The mechanochemical activation of a pyrimidine dimer.Chemical science · 2026Article
- Ultrasound-Activated Prodrugs for Precision Cancer Therapy: From Mechanical and Cavitation Effects to Advanced Sonochemical Activation.Chem & bio engineering · 2026Review
- Modification-Response Integrated Modules Driven Cyclization-Dependent Prodrug Self-Assembly for Reshaping Pro-Apoptotic Tumor Redox Homeostasis.Exploration (Beijing, China) · 2026Article
- Recent advances in tumor-activated prodrug nanoparticles for cancer immunotherapy.Frontiers in immunology · 2026Review
- High-Throughput Discovery of Ferrocene Mechanophores with Enhanced Reactivity and Network Toughening.ACS central science · 2025Article
- Logic-Gated Release of a Dual Payload from a β-Lactam Mechanophore with a Rotaxane Actuator.Angewandte Chemie (International ed. in English) · 2025Article
- Remote Control of Eukaryotic Gene Expression by a Modular Ultrasound-Responsive RNA Toolkit.Angewandte Chemie (International ed. in English) · 2025Article
- Mechanochromic Break Points Control the Toughness of Entangled Polyphenylenes.ACS macro letters · 2025Article
- The Role of Torsion on the Force-Coupled Reactivity of a Fluorenyl Naphthopyran Mechanophore.Journal of the American Chemical Society · 2025Article
- Ultrasound-Controlled Prodrug Activation: Emerging Strategies in Polymer Mechanochemistry and Sonodynamic Therapy.ACS applied bio materials · 2024Review
- Incorporation of a self-immolative spacer enables mechanically triggered dual payload release.Chemical science · 2024Article
- Multimechanophore Polymers for Mechanically Triggered Small Molecule Release with Ultrahigh Payload Capacity.Journal of the American Chemical Society · 2024Article
- Polymeric materials for ultrasound imaging and therapy.Chemical science · 2023Review
- Sono-processes: Emerging systems and their applicability within the (bio-)medical field.Ultrasonics sonochemistry · 2023Review
- Remote control of mechanochemical reactions under physiological conditions using biocompatible focused ultrasound.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Sonopharmacology: controlling pharmacotherapy and diagnosis by ultrasound-induced polymer mechanochemistry.Chemical science · 2022Review
- Force ahead: Emerging Applications and Opportunities of Polymer Mechanochemistry.ACS polymers Au · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Drug delivery systems responsive to physicochemical stimuli allow spatiotemporal control over drug activity to overcome limitations of systemic drug administration. Alongside, the non-invasive real-time tracking of drug release and uptake remains challenging as pharmacophore and reporter function are rarely unified within one molecule. Here, we present an ultrasound-responsive release system based on the mechanochemically induced 5-
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.