Evidence map›Paper›PMID 34163906›Full record

ArticleChemical science2020

Mechanism of inhibition of SARS-CoV-2 M

Kemel Arafet, Natalia Serrano-Aparicio, Alessio Lodola, Adrian J Mulholland, Florenci V González, Katarzyna Świderek, Vicent Moliner

Abstract read
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed.

  1. The pivotal role of β-lactone stereochemistry in the development of SARS-CoV-2 MProtein science : a publication of the Protein Society · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Discovery of benzyl carbamate inhibitors of coronavirus MJournal of enzyme inhibition and medicinal chemistry · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. CHARMM-GUIJournal of chemical theory and computation · 2025
    Article
  11. Identifying Inhibitor-SARS-CoV2-3CLMolecules (Basel, Switzerland) · 2025
    Article
  12. (Molecules (Basel, Switzerland) · 2024
    Article
  13. Article
  14. Review
  15. Michael Acceptors as Anti-Cancer Compounds: Coincidence or Causality?International journal of molecular sciences · 2024
    Review
  16. Article
  17. Review
  18. Article
  19. A potential allosteric inhibitor of SARS-CoV-2 main protease (MFrontiers in molecular biosciences · 2024
    Article
  20. Review

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kemel ArafetDepartament de Química Física i Analítica, Universitat Jaume I 12071 Castelló Spain swiderek@uji.es moliner@uji.es.ORCID https://orcid.org/0000-0002-0569-7332
Natalia Serrano-AparicioDepartament de Química Física i Analítica, Universitat Jaume I 12071 Castelló Spain swiderek@uji.es moliner@uji.es.ORCID https://orcid.org/0000-0002-4429-8940
Alessio LodolaDipartimento di Scienze degli Alimenti e del Farmaco, Università degli Studi di Parma Italy.ORCID https://orcid.org/0000-0002-8675-1002
Adrian J MulhollandCentre for Computational Chemistry, School of Chemistry, University of Bristol UK.ORCID https://orcid.org/0000-0003-1015-4567
Florenci V GonzálezDepartament de Química Inorgànica i Orgànica, Universitat Jaume I 12071 Castelló Spain.ORCID https://orcid.org/0000-0001-5709-734X
Katarzyna ŚwiderekDepartament de Química Física i Analítica, Universitat Jaume I 12071 Castelló Spain swiderek@uji.es moliner@uji.es.ORCID https://orcid.org/0000-0002-7528-1551
Vicent MolinerDepartament de Química Física i Analítica, Universitat Jaume I 12071 Castelló Spain swiderek@uji.es moliner@uji.es.ORCID https://orcid.org/0000-0002-3665-3391

Funding

Biotechnology and Biological Sciences Research Council BB/L01386X/1
6 · The paper itself

Abstract

The SARS-CoV-2 main protease (M

Identifiers

PMID34163906
PMCPMC8179034

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.