Evidence map›Paper›PMID 34163845›Full record

ArticleChemical science2021

Covalent and non-covalent albumin binding of Au(i) bis-NHCs

Sajal Sen, Mark W Perrin, Adam C Sedgwick, Vincent M Lynch, Jonathan L Sessler, Jonathan F Arambula

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sajal SenDepartment of Chemistry, The University of Texas at Austin 105 E 24th Street A5300 Austin TX 78712-1224 USA sessler@cm.utexas.edu jfarambula@cm.utexas.edu.ORCID https://orcid.org/0000-0002-1189-4156
Mark W PerrinDepartment of Chemistry, The University of Texas at Austin 105 E 24th Street A5300 Austin TX 78712-1224 USA sessler@cm.utexas.edu jfarambula@cm.utexas.edu.
Adam C SedgwickDepartment of Chemistry, The University of Texas at Austin 105 E 24th Street A5300 Austin TX 78712-1224 USA sessler@cm.utexas.edu jfarambula@cm.utexas.edu.ORCID https://orcid.org/0000-0002-3132-2913
Vincent M LynchDepartment of Chemistry, The University of Texas at Austin 105 E 24th Street A5300 Austin TX 78712-1224 USA sessler@cm.utexas.edu jfarambula@cm.utexas.edu.
Jonathan L SesslerDepartment of Chemistry, The University of Texas at Austin 105 E 24th Street A5300 Austin TX 78712-1224 USA sessler@cm.utexas.edu jfarambula@cm.utexas.edu.ORCID https://orcid.org/0000-0002-9576-1325
Jonathan F ArambulaDepartment of Chemistry, The University of Texas at Austin 105 E 24th Street A5300 Austin TX 78712-1224 USA sessler@cm.utexas.edu jfarambula@cm.utexas.edu.ORCID https://orcid.org/0000-0003-2342-8440
The University of Texas at Austin · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent decades have witnessed the emergence of Au(i) bis-N-heterocyclic carbenes (NHCs) as potential anticancer agents. However, these systems exhibit little interaction with serum proteins (

Identifiers

PMID34163845
PMCPMC8171490
OpenAlexW3159115226

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.