Evidence map›Paper›PMID 34163824›Full record

ArticleChemical science2021

Stealth nanorods

John R Finnegan, Emily H Pilkington, Karen Alt, Md Arifur Rahim, Stephen J Kent, Thomas P Davis, Kristian Kempe

Abstract read
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

John R FinneganARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University Parkville Victoria 3052 Australia kristian.kempe@monash.edu.ORCID https://orcid.org/0000-0002-2848-5025
Emily H PilkingtonARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University Parkville Victoria 3052 Australia kristian.kempe@monash.edu.ORCID https://orcid.org/0000-0002-4202-839X
Karen AltNanoTheranostics Laboratory, Australian Centre for Blood Diseases, Monash University Melbourne Victoria 3004 Australia.ORCID https://orcid.org/0000-0002-6252-1931
Md Arifur RahimSchool of Chemical Engineering, University of New South Wales (UNSW) Sydney NSW 2052 Australia.ORCID https://orcid.org/0000-0002-7994-2097
Stephen J KentARC Centre of Excellence in Convergent Bio-Nano Science, Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne Parkville Victoria 3010 Australia.ORCID https://orcid.org/0000-0002-8539-4891
Thomas P DavisARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University Parkville Victoria 3052 Australia kristian.kempe@monash.edu.ORCID https://orcid.org/0000-0003-2581-4986
Kristian KempeARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University Parkville Victoria 3052 Australia kristian.kempe@monash.edu.ORCID https://orcid.org/0000-0002-0136-9403

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The morphology of nanomaterials critically influences their biological interactions. However, there is currently a lack of robust methods for preparing non-spherical particles from biocompatible materials. Here, we combine 'living' crystallisation-driven self-assembly (CDSA), a seeded growth method that enables the preparation of rod-like polymer nanoparticles, with poly(2-oxazoline)s (POx), a polymer class that exhibits 'stealth' behaviour and excellent biocompatibility. For the first time, the 'living' CDSA process was carried out in pure water, resulting in POx nanorods with lengths ranging from ∼60 to 635 nm.

Identifiers

PMID34163824
PMCPMC8171341

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.