Evidence map›Paper›PMID 34163730›Full record

ArticleChemical science2021

A generator of peroxynitrite activatable with red light.

Cristina Parisi, Mariacristina Failla, Aurore Fraix, Luca Menilli, Francesca Moret, Elena Reddi, Barbara Rolando, Francesca Spyrakis, Loretta Lazzarato, Roberta Fruttero and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cristina ParisiPhotoChemLab, Department of Drug and Health Sciences, University of Catania I-95125 Italy ssortino@unict.it.ORCID https://orcid.org/0000-0002-7285-9442
Mariacristina FaillaDepartment of Science and Drug Technology, University of Torino I-10125 Torino Italy Loretta.lazzarato@unito.it.ORCID https://orcid.org/0000-0002-2318-2332
Aurore FraixPhotoChemLab, Department of Drug and Health Sciences, University of Catania I-95125 Italy ssortino@unict.it.ORCID https://orcid.org/0000-0002-8328-3290
Luca MenilliDepartment of Biology, University of Padova I-35131 Padova Italy.ORCID https://orcid.org/0000-0003-2774-6411
Francesca MoretDepartment of Biology, University of Padova I-35131 Padova Italy.ORCID https://orcid.org/0000-0002-1534-3714
Elena ReddiDepartment of Biology, University of Padova I-35131 Padova Italy.ORCID https://orcid.org/0000-0002-7360-9138
Barbara RolandoDepartment of Science and Drug Technology, University of Torino I-10125 Torino Italy Loretta.lazzarato@unito.it.
Francesca SpyrakisDepartment of Science and Drug Technology, University of Torino I-10125 Torino Italy Loretta.lazzarato@unito.it.
Loretta LazzaratoDepartment of Science and Drug Technology, University of Torino I-10125 Torino Italy Loretta.lazzarato@unito.it.ORCID https://orcid.org/0000-0001-7100-8593
Roberta FrutteroDepartment of Science and Drug Technology, University of Torino I-10125 Torino Italy Loretta.lazzarato@unito.it.
Alberto GascoDepartment of Science and Drug Technology, University of Torino I-10125 Torino Italy Loretta.lazzarato@unito.it.
Salvatore SortinoPhotoChemLab, Department of Drug and Health Sciences, University of Catania I-95125 Italy ssortino@unict.it.ORCID https://orcid.org/0000-0002-2086-1276

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The generation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) as "unconventional" therapeutics with precise spatiotemporal control by using light stimuli may open entirely new horizons for innovative therapeutic modalities. Among ROS and RNS, peroxynitrite (ONOO

Identifiers

PMID34163730
PMCPMC8179535

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.