Evidence map›Paper›PMID 34163724›Full record

ArticleChemical science2021

Tailoring the optical and dynamic properties of iminothioindoxyl photoswitches through acidochromism.

Miroslav Medved', Mark W H Hoorens, Mariangela Di Donato, Adèle D Laurent, Jiayun Fan, Maria Taddei, Michiel Hilbers, Ben L Feringa, Wybren Jan Buma, Wiktor Szymanski

Abstract read
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Monodirectional Photocycle Drives Proton Translocation.Journal of the American Chemical Society · 2023
    Article
  6. Thermal and (Thermo-Reversible) Photochemical Cycloisomerization of 1Journal of the American Chemical Society · 2023
    Article
  7. Optical Modulation of Antibiotic Resistance by Photoswitchable Cystobactamids.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022
    Article
  8. Article
  9. Molecular photoswitches in aqueous environments.Chemical Society reviews · 2021
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Miroslav Medved'Regional Centre of Advanced Technologies and Materials, Faculty of Science, Palacký University in Olomouc Šlechtitelů 27 CZ-771 46 Olomouc Czech Republic miroslav.medved@umb.sk.ORCID https://orcid.org/0000-0001-8599-1031
Mark W H HoorensUniversity Medical Center Groningen, Department of Radiology, Medical Imaging Center, University of Groningen Hanzeplein 1 9713 GZ Groningen The Netherlands w.szymanski@umcg.nl.
Mariangela Di DonatoEuropean Laboratory for Non Linear Spectroscopy (LENS) via N. Carrara 1 50019 Sesto Fiorentino Italy.ORCID https://orcid.org/0000-0002-6596-7031
Adèle D LaurentLaboratoire CEISAM UMR UN-CNRS 6230, Université de Nantes Nantes F-44000 France.ORCID https://orcid.org/0000-0001-9553-9014
Jiayun FanVan't Hoff Institute for Molecular Sciences, University of Amsterdam Science Park 904 1098 XH Amsterdam The Netherlands.
Maria TaddeiEuropean Laboratory for Non Linear Spectroscopy (LENS) via N. Carrara 1 50019 Sesto Fiorentino Italy.
Michiel HilbersVan't Hoff Institute for Molecular Sciences, University of Amsterdam Science Park 904 1098 XH Amsterdam The Netherlands.
Ben L FeringaCentre for Systems Chemistry, Stratingh Institute for Chemistry, Faculty of Science and Engineering, University of Groningen Nijenborgh 7 9747 AG Groningen The Netherlands.ORCID https://orcid.org/0000-0003-0588-8435
Wybren Jan BumaVan't Hoff Institute for Molecular Sciences, University of Amsterdam Science Park 904 1098 XH Amsterdam The Netherlands.ORCID https://orcid.org/0000-0002-1265-8016
Wiktor SzymanskiUniversity Medical Center Groningen, Department of Radiology, Medical Imaging Center, University of Groningen Hanzeplein 1 9713 GZ Groningen The Netherlands w.szymanski@umcg.nl.ORCID https://orcid.org/0000-0002-9754-9248

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multi-responsive functional molecules are key for obtaining user-defined control of the properties and functions of chemical and biological systems. In this respect, pH-responsive photochromes, whose switching can be directed with light and acid-base equilibria, have emerged as highly attractive molecular units. The challenge in their design comes from the need to accommodate application-defined boundary conditions for both light- and protonation-responsivity. Here we combine time-resolved spectroscopic studies, on time scales ranging from femtoseconds to seconds, with density functional theory (DFT) calculations to elucidate and apply the acidochromism of a recently designed iminothioindoxyl (ITI) photoswitch. We show that protonation of the thermally stable

Identifiers

PMID34163724
PMCPMC8179557

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.