ReviewChemical science2021
Water as the reaction medium in organic chemistry: from our worst enemy to our best friend.
Review in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
95 citing papers in PubMed.
- Pushing C-N bond formation in water: sustainable strategies, mechanistic roles and future perspectives.RSC advances · 2026Review
- Mechanistic questions in aqueous-organic chemistry.Nature reviews. Chemistry · 2026Review
- Sustainable Pd-Catalyzed Aminations "on Dirty Water".Angewandte Chemie (International ed. in English) · 2026Article
- Rapid assembly of structurally diverse 3,4-dihydroquinazolines with anticancer activity via SDS-promoted aqueous synthesis.Molecular diversity · 2026Article
- Development of Membrane Transport-Inspired Biomimetic System to Degrade Plasticizers.Chemistry, an Asian journal · 2026Article
- Review
- Effects of "On-Water" on the Free Radical Polymerization of Methacrylates.Langmuir : the ACS journal of surfaces and colloids · 2026Article
- Stimuli-Responsive Silsesquioxane Nanozymes for Organocatalysis in Water and Prodrug Activation in Cells.Angewandte Chemie (International ed. in English) · 2026Article
- Micellar effects upon synthesis of 1,2-dihydro-1-arylnaphtho[1,2-RSC advances · 2026Article
- Merging Micellar Catalysis and C-H Activation: Silver-Free Direct Arylation of Fluoroarenes in Water.ChemSusChem · 2026Article
- Nuclear Quantum Effects on the Dynamics of Bulk Water and Supercooled Aqueous Solutions.The journal of physical chemistry letters · 2026Article
- Recent Developments in Sustainable Solubilization.ChemSusChem · 2026Article
- Development of Mild Palladium-Catalyzed N-Arylation of Ortho-Acylanilines in Rhamnolipid Micellar System.ChemSusChem · 2026Article
- Nanoassembly-enabled aqueous solid-phase peptide synthesis (ASPPS): a practical DMF-free approach based on the Fmoc strategy.RSC advances · 2026Article
- Microwave-Assisted Organic Syntheses in Deep Eutectic Solvents: A Win-Win Association for Sustainable Chemistry.ChemistryOpen · 2026Review
- Expanding amide bond formation with CaLB-BOP: from sterically hindered substrates to aqueous and micellar media.RSC advances · 2026Article
- Sustainable and Scalable Redesign of PS-750-M Synthesis While Retaining Micellar Catalytic Efficiency.ACS sustainable chemistry & engineering · 2026Article
- NMR and DFT Studies on Solvation Phenomena in Bioorganic Molecules, Natural Products and Model Compounds: Current and Future Perspectives for Atomic-Level Structures and Mechanistic Catalytic Reactions.Molecules (Basel, Switzerland) · 2026Article
- "On-water" photosensitization enables redox neutral acylation and alkylation of quinones.Nature communications · 2026Article
- Direct diazotization of indoles with 2-Methoxyethyl nitrite.Communications chemistry · 2026Article
35 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A review presenting water as the logical reaction medium for the future of organic chemistry. A discussion is offered that covers both the "on water" and "in water" phenomena, and how water is playing unique roles in each, specifically with regard to its use in organic synthesis.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.