Evidence map›Paper›PMID 34163679›Full record

ArticleChemical science2021

Albumin-mediated alteration of plasma zinc speciation by fatty acids modulates blood clotting in type-2 diabetes.

Amélie I S Sobczak, Kondwani G H Katundu, Fladia A Phoenix, Siavash Khazaipoul, Ruitao Yu, Fanuel Lampiao, Fiona Stefanowicz, Claudia A Blindauer, Samantha J Pitt, Terry K Smith and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Properties of the major ZnChemical communications (Cambridge, England) · 2025
    Article
  3. Trace Elements in Medicinal Metallomics.Mini reviews in medicinal chemistry · 2025
    Review
  4. EPR spectroscopic characterisation of native CuDalton transactions (Cambridge, England : 2003) · 2024
    Article
  5. Review
  6. ZnInternational journal of molecular sciences · 2023
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Strategies for Therapeutic Amelioration of Aberrant Plasma ZnInternational journal of molecular sciences · 2022
    Review
  12. Albumin-mediated extracellular zinc speciation drives cellular zinc uptake.Chemical communications (Cambridge, England) · 2022
    Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 5 countries.

Amélie I S SobczakSchool of Medicine, University of St Andrews Fife KY16 9TF St Andrews UK ajs21@st-andrews.ac.uk +44 (0)1334 463482 +44 (0)1334 463546.ORCID https://orcid.org/0000-0003-4892-7203
Kondwani G H KatunduSchool of Medicine, University of St Andrews Fife KY16 9TF St Andrews UK ajs21@st-andrews.ac.uk +44 (0)1334 463482 +44 (0)1334 463546.
Fladia A PhoenixLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds Leeds UK.
Siavash KhazaipoulSchool of Medicine, University of St Andrews Fife KY16 9TF St Andrews UK ajs21@st-andrews.ac.uk +44 (0)1334 463482 +44 (0)1334 463546.
Ruitao YuSchool of Medicine, University of St Andrews Fife KY16 9TF St Andrews UK ajs21@st-andrews.ac.uk +44 (0)1334 463482 +44 (0)1334 463546.
Fanuel LampiaoCollege of Medicine, University of Malawi Blantyre Malawi.
Fiona StefanowiczScottish Trace Element and Micronutrient Diagnostic and Research Laboratory, Department of Biochemistry NHS Greater Glasgow and Clyde Glasgow UK.
Claudia A BlindauerDepartment of Chemistry, University of Warwick Coventry UK.ORCID https://orcid.org/0000-0001-8396-9332
Samantha J PittSchool of Medicine, University of St Andrews Fife KY16 9TF St Andrews UK ajs21@st-andrews.ac.uk +44 (0)1334 463482 +44 (0)1334 463546.ORCID https://orcid.org/0000-0003-2257-1595
Terry K SmithSchool of Biology, Biomedical Sciences Research Complex, University of St Andrews St Andrews UK.
Ramzi A AjjanLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds Leeds UK.
Alan J StewartSchool of Medicine, University of St Andrews Fife KY16 9TF St Andrews UK ajs21@st-andrews.ac.uk +44 (0)1334 463482 +44 (0)1334 463546.ORCID https://orcid.org/0000-0003-4580-1840
St. Andrews University · USUniversity of Leeds · GBNHS Greater Glasgow and Clyde · GBUniversity of Malawi · MWUniversity of Warwick · GB

Funding

British Heart Foundation FS/15/42/31556British Heart Foundation PG/15/9/31270
6 · The paper itself

Abstract

Zn

Identifiers

PMID34163679
PMCPMC8179462
OpenAlexW3128738139

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.