Evidence map›Paper›PMID 34163435›Full record

ArticleFrontiers in endocrinology2021

Modelling of Epithelial Growth, Fission and Lumen Formation During Embryonic Thyroid Development: A Combination of Computational and Experimental Approaches.

Leolo Gonay, Catherine Spourquet, Matthieu Baudoin, Ludovic Lepers, Pascale Lemoine, Alexander G Fletcher, Emmanuel Hanert, Christophe E Pierreux

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Biophysics of lumen morphogenesis.Development (Cambridge, England) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Leolo GonayEarth and Life Institute, UCLouvain, Louvain-La-Neuve, Belgium.
Catherine Spourquetde Duve Institute, UCLouvain, Woluwé-Saint-Lambert, Belgium.
Matthieu BaudoinEarth and Life Institute, UCLouvain, Louvain-La-Neuve, Belgium.
Ludovic LepersEarth and Life Institute, UCLouvain, Louvain-La-Neuve, Belgium.
Pascale Lemoinede Duve Institute, UCLouvain, Woluwé-Saint-Lambert, Belgium.
Alexander G FletcherSchool of Mathematics and Statistics, University of Sheffield, Sheffield, United Kingdom.
Emmanuel HanertEarth and Life Institute, UCLouvain, Louvain-La-Neuve, Belgium.
Christophe E Pierreuxde Duve Institute, UCLouvain, Woluwé-Saint-Lambert, Belgium.
de Duve Institute · BEUCLouvain · BEUniversity of Sheffield · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organogenesis is the phase of embryonic development leading to the formation of fully functional organs. In the case of the thyroid, organogenesis starts from the endoderm and generates a multitude of closely packed independent spherical follicular units surrounded by a dense network of capillaries. Follicular organisation is unique and essential for thyroid function,

Indexed as

Computer SimulationEmbryonic DevelopmentMorphogenesisOrganogenesisAnimalsEmbryo, MammalianEndothelial CellsEpithelial CellsImage Processing, Computer-AssistedMiceModels, TheoreticalThyroid Glandepithelialmodellingmorphogenesisthyroidvertex model

Identifiers

PMID34163435
PMCPMC8216395
OpenAlexW3166596718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.