Evidence map›Paper›PMID 34163434›Full record

ArticleFrontiers in endocrinology2021

The Impact of

Daniel J Cuthbertson, Jorge Barriuso, Angela Lamarca, Prakash Manoharan, Thomas Westwood, Matthew Jaffa, Stephen W Fenwick, Christina Nuttall, Fiona Lalloo, Andreas Prachalias and 12 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. American Association of Clinical Endocrinology Consensus Statement on Management of Multiple Endocrine Neoplasia Type 1.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2025
    Guideline
  2. Article
  3. Review
  4. Endocrine oncology (Bristol, England) · 2025
    Article
  5. Review
  6. Article
  7. Diagnosis and management of neuroendocrine tumours.Clinical medicine (London, England) · 2023
    Article
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 9 institutions in 1 country.

Daniel J CuthbertsonLiverpool University Hospitals NHS Foundation Trust, ENETS Centre of Excellence, Liverpool, United Kingdom.
Jorge BarriusoDivision of Cancer Sciences, University of Manchester, Manchester, United Kingdom.
Angela LamarcaDivision of Cancer Sciences, University of Manchester, Manchester, United Kingdom.
Prakash ManoharanDepartment of Radiology and Nuclear Medicine, The Christie NHS Foundation Trust ENETS Centre of Excellence, Manchester, United Kingdom.
Thomas WestwoodDepartment of Radiology and Nuclear Medicine, The Christie NHS Foundation Trust ENETS Centre of Excellence, Manchester, United Kingdom.
Matthew JaffaLiverpool University Hospitals NHS Foundation Trust, ENETS Centre of Excellence, Liverpool, United Kingdom.
Stephen W FenwickLiverpool University Hospitals NHS Foundation Trust, ENETS Centre of Excellence, Liverpool, United Kingdom.
Christina NuttallDepartment of Medical Oncology, The Christie NHS Foundation Trust, ENETS Centre of Excellence, Manchester, United Kingdom.
Fiona LallooDepartment of Clinical Genetics, Manchester Centre for Genomic Medicine, Central Manchester University Hospitals NHS Foundation Trust, Saint Mary's Hospital, Manchester, United Kingdom.
Andreas PrachaliasInstitute of Liver Studies, Kings College Hospital, London, United Kingdom.
Michail PizaniasInstitute of Liver Studies, Kings College Hospital, London, United Kingdom.
Hulya WieshmannLiverpool University Hospitals NHS Foundation Trust, ENETS Centre of Excellence, Liverpool, United Kingdom.
Mairead G McNamaraDivision of Cancer Sciences, University of Manchester, Manchester, United Kingdom.
Richard HubnerDivision of Cancer Sciences, University of Manchester, Manchester, United Kingdom.
Raj SrirajaskanthanNeuroendocrine Tumour Unit, KHP ENETS Centre of Excellence, Institute of Liver Studies, Kings College Hospital, London, United Kingdom.
Gillian VivianNeuroendocrine Tumour Unit, KHP ENETS Centre of Excellence, Institute of Liver Studies, Kings College Hospital, London, United Kingdom.
John RamageNeuroendocrine Tumour Unit, KHP ENETS Centre of Excellence, Institute of Liver Studies, Kings College Hospital, London, United Kingdom.
Martin O WeickertThe Arden Neuroendocrine Centre, ENETS Centre of Excellence, University Hospitals Coventry and Warwickshire, Coventry, United Kingdom.
D Mark PritchardLiverpool University Hospitals NHS Foundation Trust, ENETS Centre of Excellence, Liverpool, United Kingdom.
Sobhan VinjamuriLiverpool University Hospitals NHS Foundation Trust, ENETS Centre of Excellence, Liverpool, United Kingdom.
Juan ValleDivision of Cancer Sciences, University of Manchester, Manchester, United Kingdom.
Vincent S YipBarts and the London HPB Centre, Royal London Hospital, London, United Kingdom.
King's College Hospital · GBThe Christie NHS Foundation Trust · GBAintree University Hospitals NHS Foundation Trust · GBUniversity of Liverpool · GBUniversity of Manchester · GBCancer Research UK Manchester Institute · GBRoyal Liverpool University Hospital · GBSt Mary's Hospital · GBUniversity Hospitals Coventry and Warwickshire NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Pancreatic neuroendocrine tumours (panNETs) arise sporadically or as part of a genetic predisposition syndrome. CT/MRI, endoscopic ultrasonography and functional imaging using Octreoscan localise and stage disease. This study aimed to evaluate the complementary role of Design: A retrospective study conducted across three tertiary UK NET referral centres. Methods: Demographic, clinical, biochemical, cross-sectional and functional imaging data were collected from patients who had undergone a Results: We collected data for 183 patients (97 male): median (SD) age 63 (14.9) years, 89.1 Conclusion:

Indexed as

AgedChelating AgentsCross-Sectional StudiesDisease ManagementFemaleFollow-Up StudiesGallium RadioisotopesHeterocyclic Compounds, 1-RingHumansMaleMiddle AgedNeuroendocrine TumorsPancreatic NeoplasmsPositron-Emission TomographyPrognosisRadiopharmaceuticals1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidChelating AgentsGallium RadioisotopesHeterocyclic Compounds, 1-RingRadiopharmaceuticals68Gallium DOTA PET/CTfunctional imagingmultiple endocrine neoplasia type 1pancreatic neuroendocrine tumourssporadic and familial

Identifiers

PMID34163434
PMCPMC8215358
OpenAlexW3171572165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.