Evidence map›Paper›PMID 34163382›Full record

ArticleFrontiers in psychiatry2021

Increased Glutamate Plus Glutamine in the Right Middle Cingulate in Early Schizophrenia but Not in Bipolar Psychosis: A Whole Brain

Juan R Bustillo, Elizabeth G Mayer, Joel Upston, Thomas Jones, Crystal Garcia, Sulaiman Sheriff, Andrew Maudsley, Mauricio Tohen, Charles Gasparovic, Rhoshel Lenroot

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Glutamatergic dysfunction in Schizophrenia.Translational psychiatry · 2022
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Juan R BustilloDepartment of Psychiatry and Behavioral Sciences, University of New Mexico, Albuquerque, NM, United States.
Elizabeth G MayerDepartment of Psychiatry and Behavioral Sciences, University of New Mexico, Albuquerque, NM, United States.
Joel UpstonDepartment of Psychiatry and Behavioral Sciences, University of New Mexico, Albuquerque, NM, United States.
Thomas JonesDepartment of Psychiatry and Behavioral Sciences, University of New Mexico, Albuquerque, NM, United States.
Crystal GarciaDepartment of Psychiatry and Behavioral Sciences, University of New Mexico, Albuquerque, NM, United States.
Sulaiman SheriffDepartment of Radiology, University of Miami, Miami, FL, United States.
Andrew MaudsleyDepartment of Radiology, University of Miami, Miami, FL, United States.
Mauricio TohenDepartment of Psychiatry and Behavioral Sciences, University of New Mexico, Albuquerque, NM, United States.
Charles GasparovicMind Research Network, Albuquerque, NM, United States.
Rhoshel LenrootDepartment of Psychiatry and Behavioral Sciences, University of New Mexico, Albuquerque, NM, United States.
University of New Mexico · USUniversity of Miami · USMind Research Network · US

Funding

NEURAL MECHANISMS OF SCHIZOPHRENIAP20RR021938 · NCRR · THE MIND RESEARCH NETWORK · PI HANLON, FAITH MARIE · 2008 to 2011
$9.4M
UNIVERSITY OF NEW MEXICO CLINICAL AND TRANSLATIONAL SCIENCE CENTERUL1RR031977 · NCRR · UNIVERSITY OF NEW MEXICO · PI LARSON, RICHARD S · 2010 to 2011
$8.8M
Development and Maintenance of Software for MR Spectroscopic ImagingR01EB016064 · NIBIB · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI MAUDSLEY, ANDREW A. · 2013 to 2021
$2.0M
Brain Glutamate and Outcome in SchizophreniaR01MH084898 · NIMH · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI BUSTILLO, JUAN RICARDO · 2009 to 2013
$1.7M
NCRR NIH HHS P20 RR021938NCRR NIH HHS UL1 RR031977NIBIB NIH HHS R01 EB016064NIMH NIH HHS R01 MH084898
6 · The paper itself

Abstract

Proton magnetic resonance spectroscopy (

Indexed as

bipolarcholinecreatineglutamateN-acetyl-aspartatepsychosisschizophreniaspectroscopy

Identifiers

PMID34163382
PMCPMC8215955
OpenAlexW3169639950

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.