Evidence map›Paper›PMID 34163367›Full record

ReviewFrontiers in pharmacology2021

The Application of and Strategy for Gold Nanoparticles in

Jia-Shuai He, Shi-Jin Liu, Yi-Ran Zhang, Xiao-Dong Chu, Zheng-Bin Lin, Zhan Zhao, Sheng-Hui Qiu, Yan-Guan Guo, Hui Ding, Yun-Long Pan and 1 more

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Review
  2. Review
  3. Advancing brain immunotherapy through functional nanomaterials.Drug delivery and translational research · 2026
    Review
  4. Review
  5. Natural carrier systems in cancer vaccines and immunotherapy.Human vaccines & immunotherapeutics · 2025
    Review
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jia-Shuai HeDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Shi-Jin LiuDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Yi-Ran ZhangDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Xiao-Dong ChuDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Zheng-Bin LinDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Zhan ZhaoDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Sheng-Hui QiuDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Yan-Guan GuoDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Hui DingDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Yun-Long PanDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Jing-Hua PanDepartment of General Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapy of malignant tumor is a verified and crucial anti-tumor strategy to help patients with cancer for prolonging prognostic survival. It is a novel anticancer tactics that activates the immune system to discern and damage cancer cells, thereby prevent them from proliferating. However, immunotherapy still faces many challenges in view of clinical efficacy and safety issues. Various nanomaterials, especially gold nanoparticles (AuNPs), have been developed not only for anticancer treatment but also for delivering antitumor drugs or combining other treatment strategies. Recently, some studies have focused on AuNPs for enhancing cancer immunotherapy. In this review, we summarized how AuNPs applicated as immune agents, drug carriers or combinations with other immunotherapies for anticancer treatment. AuNPs can not only act as immune regulators but also deliver immune drugs for cancer. Therefore, AuNPs are candidates for enhancing the efficiency and safety of cancer immunotherapy.

Indexed as

cancer immunotherapydrug delivery systemgold nanoparticlesnanocarriersnanomaterials

Identifiers

PMID34163367
PMCPMC8215714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.