Evidence map›Paper›PMID 34163350›Full record

ArticleFrontiers in aging neuroscience2021

Impaired Executive Function and Depression as Independent Risk Factors for Reported Delirium Symptoms: An Observational Cohort Study Over 8 Years.

Christian Mychajliw, Matthias L Herrmann, Ulrike Suenkel, Katharina Brand, Anna-Katharina von Thaler, Isabel Wurster, Rezzak Yilmaz, Gerhard W Eschweiler, Florian G Metzger

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Christian MychajliwDepartment of Psychiatry and Psychotherapy, University Hospital of Tübingen, Tübingen, Germany.
Matthias L HerrmannDepartment of Psychiatry and Psychotherapy, University Hospital of Tübingen, Tübingen, Germany.
Ulrike SuenkelDepartment of Psychiatry and Psychotherapy, University Hospital of Tübingen, Tübingen, Germany.
Katharina BrandGeriatric Center, University Hospital of Tübingen, Tübingen, Germany.
Anna-Katharina von ThalerDepartment of Neurology, University Medical Center Schleswig-Holstein, Kiel, Germany.
Isabel WursterDepartment of Neurology, University Hospital of Tübingen, Tübingen, Germany.
Rezzak YilmazDepartment of Neurology, University of Ankara Medical School, Ankara, Turkey.
Gerhard W EschweilerDepartment of Psychiatry and Psychotherapy, University Hospital of Tübingen, Tübingen, Germany.
Florian G MetzgerDepartment of Psychiatry and Psychotherapy, University Hospital of Tübingen, Tübingen, Germany.
University Children's Hospital Tübingen · DEAnkara University · TRUniversity Hospital Schleswig-Holstein · DEUniversity of Freiburg · DEVitos · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute medical illnesses, surgical interventions, or admissions to hospital in older individuals are frequently associated with a delirium. In this cohort study, we investigated the impact of specific cognitive domains and depression before the occurrence of delirium symptoms in an 8-year observation of older non-hospitalized individuals.

methodsIn total, we included 807 participants (48-83 years). Deficits in specific cognitive domains were measured using the CERAD test battery, and depressive symptoms were measured using Beck Depression Inventory and the Geriatric Depression Scale (GDS) before the onset of a delirium. Delirium symptoms were retrospectively assessed by a questionnaire based on the established Nursing Delirium Screening Scale.

resultsFifty-eight of eight hundred seven participants (7.2%) reported delirium symptoms over the 8-year course of the study. Sixty-nine percent (

conclusionEspecially prior to elective surgery or medical interventions, screening for impaired executive function and depression could be helpful to identify patients who are at risk to develop delirium symptoms.

Indexed as

acute encephalopathycognitioncognitive functionscohort studydeliriumdepressionexecutive functionobservational study

Identifiers

PMID34163350
PMCPMC8215445
OpenAlexW3168106748

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.