Evidence map›Paper›PMID 34163329›Full record

ReviewFrontiers in cellular neuroscience2021

Calcium Signals in Astrocyte Microdomains, a Decade of Great Advances.

Annamaria Lia, Vanessa Jorge Henriques, Micaela Zonta, Angela Chiavegato, Giorgio Carmignoto, Marta Gómez-Gonzalo, Gabriele Losi

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 87 citations in OpenAlex.

  1. Review
  2. Prolonged systemic inflammation worsens impairments to astrocyte CaAlzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Mitochondrial CaBiomolecules · 2026
    Review
  8. Article
  9. Review
  10. Article
  11. Prolonged systemic inflammation worsens impairments to astrocyte CabioRxiv : the preprint server for biology · 2025
    Article
  12. Review
  13. Article
  14. Review
  15. Astrocytes in Rodent Anxiety-Related Behavior: Role of Calcium and Beyond.International journal of molecular sciences · 2025
    Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Annamaria LiaNeuroscience Institute, National Research Council (IN-CNR), Padua, Italy.
Vanessa Jorge HenriquesNeuroscience Institute, National Research Council (IN-CNR), Padua, Italy.
Micaela ZontaNeuroscience Institute, National Research Council (IN-CNR), Padua, Italy.
Angela ChiavegatoDepartment of Biomedical Sciences, University of Padua, Padua, Italy.
Giorgio CarmignotoNeuroscience Institute, National Research Council (IN-CNR), Padua, Italy.
Marta Gómez-GonzaloNeuroscience Institute, National Research Council (IN-CNR), Padua, Italy.
Gabriele LosiNeuroscience Institute, National Research Council (IN-CNR), Padua, Italy.
National Research Council · ITNeuroscience Institute · ITUniversity of Padua · ITNational Academies of Sciences, Engineering, and Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The glial cells astrocytes have long been recognized as important neuron-supporting elements in brain development, homeostasis, and metabolism. After the discovery that the reciprocal communication between astrocytes and neurons is a fundamental mechanism in the modulation of neuronal synaptic communication, over the last two decades astrocytes became a hot topic in neuroscience research. Crucial to their functional interactions with neurons are the cytosolic Ca

Indexed as

astrocytescalciumgliotransmissionmicrodomainstripartite synapses

Identifiers

PMID34163329
PMCPMC8216559
OpenAlexW3166386104

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.