Evidence map›Paper›PMID 34163273›Full record

ArticleNature and science of sleep2021

Setting Objective Clinical Assessment Tools for Circadian Rhythm Sleep-Wake Disorders - A Community-Based Cross-Sectional Epidemiological Study.

Frangiskos Frangopoulos, Ivi Nicolaou, Savvas Zannetos, Nicholas-Tiberio Economou, Tonia Adamide, Andreas Georgiou, Pantelis Theodoros Nikolaidis, Thomas Rosemann, Beat Knechtle, Georgia Trakada

Open access · goldAbstract read
In one paragraph

Article in Nature and science of sleep, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Hair Follicles as a Critical Model for Monitoring the Circadian Clock.International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Frangiskos FrangopoulosRespiratory Department, Nicosia General Hospital, Nicosia, Cyprus.
Ivi NicolaouRespiratory Department, Nicosia General Hospital, Nicosia, Cyprus.
Savvas ZannetosHealth Economics and Statistics, Neapolis University, Paphos, Cyprus.ORCID 0000-0002-2393-6667
Nicholas-Tiberio EconomouDivision of Pulmonology, Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Alexandra Hospital, Athens, Greece.
Tonia AdamideRespiratory Department, Nicosia General Hospital, Nicosia, Cyprus.
Andreas GeorgiouRespiratory Department, Nicosia General Hospital, Nicosia, Cyprus.
Pantelis Theodoros NikolaidisSchool of Health and Caring Sciences, University of West Attica, Athens, Greece.ORCID 0000-0001-8030-7122
Thomas RosemannInstitute of Primary Care, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-6436-6306
Beat KnechtleInstitute of Primary Care, University of Zurich, Zurich, Switzerland.
Georgia TrakadaDivision of Pulmonology, Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Alexandra Hospital, Athens, Greece.ORCID 0000-0003-0037-1269
Nicosia General Hospital · CYNational and Kapodistrian University of Athens · GRUniversity of Zurich · CHNeapolis University Pafos · CYUniversity of West Attica · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCircadian rhythm sleep-wake disorder (CRSWD) is an often-misdiagnosed group of sleep disturbances with limited data concerning diagnostic and therapeutic algorithms in the general population. Therefore, reported prevalence varies in the literature due to different case definitions, methodological, and environmental factors.

objectivesThe purpose of our cross-sectional study was to estimate the prevalence of CRSWD in the general population of Cyprus and to suggest clinical parameters for the assessment of atypical sleep schedules. The estimation was carried out by introducing normal preset sleep time limits, according to the imposed local environment and by administering well-established questionnaires for symptoms and consequence dysfunction, as objective evaluation tools.

methodsIn a nationwide epidemiological survey, 4118 Cypriot adult participants, selected and stratified to represent the general population, were interviewed on sleep habits and complaints by computer-assisted telephone interviewing (CATI). In the second stage, 250 adults were randomly selected from the initial representative sample, for a CRSWD assessment. According to the proposed diagnostic criteria, patients were interviewed about sleepiness and/or insomnia, and daytime dysfunction (fatigue, anxiety, and depression). They were also assessed by a weekly sleep diary for sleep schedules. Finally, all participants underwent a Type III Sleep Study, to rule out obstructive sleep apnea.

resultsFrom 195 enrolled participants (response rate 78%), 25 individuals (12.8%) met the criteria for CRSWD. The two most prevalent disorders were delayed sleep-wake phase disorder (DSWPD) (10pts, 5.1%) and shift work sleep disorder (SWD) (13, 6.7%). Less prevalent disorders included irregular sleep-wake rhythm disorder (ISWRD) (1, 0.5%) and advanced sleep-wake phase disorder (ASWPD) (1, 0.5%).

conclusionsAccording to our data, CRSWDs are common in the general population of Cyprus, especially DSWPD and SWD. Affected individuals usually suffer from sleep deprivation and complain about insomnia, sleepiness and depression.

Indexed as

circadian sleep wake phase disordersguidelinesprevalencesleep deprivation

Identifiers

PMID34163273
PMCPMC8215907
OpenAlexW3172481623

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.