Evidence map›Paper›PMID 34163204›Full record

ArticleClinical, cosmetic and investigational dermatology2021

Analysis of the Bacterial Flora of Sensitive Facial Skin Among Women in Guangzhou.

Zhifen Qiao, Shiyi Huang, Fang Leng, Yu Bei, Yingzhi Chen, Minjie Chen, Yunfeng Hu, Yadong Huang, Qi Xiang

Open access · goldAbstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Synergistic Effects of Solar Exposure and Skin Sensitivity on Skin Aging: A Clinical Study Using Multimodal Noninvasive Measurements.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2026
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zhifen Qiao *Institute of Biomedicine and Guangdong Provincial Key Laboratory of Bioengineering Medicine, Jinan University, Guangzhou, 510632, People's Republic of China.
Shiyi Huang *Institute of Biomedicine and Guangdong Provincial Key Laboratory of Bioengineering Medicine, Jinan University, Guangzhou, 510632, People's Republic of China.
Fang LengInstitute of Biomedicine and Guangdong Provincial Key Laboratory of Bioengineering Medicine, Jinan University, Guangzhou, 510632, People's Republic of China.
Yu BeiBiopharmaceutical R&D Center of Jinan University, Guangzhou, 510632, People's Republic of China.
Yingzhi ChenBiopharmaceutical R&D Center of Jinan University, Guangzhou, 510632, People's Republic of China.
Minjie ChenBiopharmaceutical R&D Center of Jinan University, Guangzhou, 510632, People's Republic of China.
Yunfeng HuThe First Affiliated Hospital of Jinan University, Department of Dermatology, Guangzhou, 510632, People's Republic of China.
Yadong HuangInstitute of Biomedicine and Guangdong Provincial Key Laboratory of Bioengineering Medicine, Jinan University, Guangzhou, 510632, People's Republic of China.ORCID 0000-0002-8879-3273
Qi XiangInstitute of Biomedicine and Guangdong Provincial Key Laboratory of Bioengineering Medicine, Jinan University, Guangzhou, 510632, People's Republic of China.
Jinan University · CNFirst Affiliated Hospital of Jinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSensitive skin (SS) is easily irritated by various environmental stimuli, and epidemiological surveys surprisingly find that self-perceived SS is widespread worldwide.

objectiveTo investigate whether SS is linked to changes in the skin bacterial population using 16S rRNA sequencing and bioinformatic analysis. PATIENTS AND

methodsAccording to both the Huaxi SS Questionnaire and Lactic Acid Stimulation Test, 60 female volunteers in Guangzhou were classified into normal skin (NS) and SS groups. Skin barrier parameters were assessed by the CK skin tester. The DNA of the bacterial flora on the facial skin surface was extracted and was subjected to 16S rRNA sequencing.

resultsThe skin hydration was significantly lower in the SS group compared to the NS group (

conclusionSS is accompanied by a decrease in species diversity and richness, which may be relevant to the weakening of the microbial barrier (due to the increase of

Indexed as

16S rRNA sequencingbacterialsensitive skinskin barrierskin microbiome

Identifiers

PMID34163204
PMCPMC8214519
OpenAlexW3167409801

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.