Evidence map›Paper›PMID 34163191›Full record

ArticleClinicoEconomics and outcomes research : CEOR2021

Economic Impact of COVID-19 Lockdown on Italian NHS: Focus on Diabetes Mellitus.

Enrico Torre, Giorgio Lorenzo Colombo, Sergio Di Matteo, Chiara Martinotti, Maria Chiara Valentino, Alberto Rebora, Francesca Cecoli, Eleonora Monti, Marco Galimberti, Paolo Di Bartolo and 2 more

Open access · goldAbstract read
In one paragraph

Article in ClinicoEconomics and outcomes research : CEOR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Enrico TorreEndocrinology Diabetology and Metabolic Diseases Unit - ASL3, Genoa, Italy.ORCID 0000-0002-4375-7383
Giorgio Lorenzo ColomboDepartment of Drug Sciences, University of Pavia, Pavia, Italy.ORCID 0000-0002-5790-8891
Sergio Di MatteoS.A.V.E. Studi Analisi Valutazioni Economiche S.r.l., Health Economics & Outcomes Research, Milan, Italy.
Chiara MartinottiS.A.V.E. Studi Analisi Valutazioni Economiche S.r.l., Health Economics & Outcomes Research, Milan, Italy.ORCID 0000-0001-6304-9977
Maria Chiara ValentinoS.A.V.E. Studi Analisi Valutazioni Economiche S.r.l., Health Economics & Outcomes Research, Milan, Italy.ORCID 0000-0002-8736-3503
Alberto ReboraEndocrinology Diabetology and Metabolic Diseases Unit - ASL3, Genoa, Italy.
Francesca CecoliEndocrinology Diabetology and Metabolic Diseases Unit - ASL3, Genoa, Italy.
Eleonora MontiEndocrinology Diabetology and Metabolic Diseases Unit - ASL3, Genoa, Italy.
Marco GalimbertiDP Trade SA, Lugano, Switzerland.ORCID 0000-0003-0917-4034
Paolo Di BartoloDiabetes Center of Ravenna, Romagna Diabetes Clinical Network, Romagna Local Health Authority, Ravenna, Italy.ORCID 0000-0001-5957-1551
Germano GaggioliCardiology Unit Villascassi Hospital - ASL3, Genoa, Italy.
Giacomo Matteo BrunoDepartment of Drug Sciences, University of Pavia, Pavia, Italy.ORCID 0000-0003-4571-654X
University of Pavia · ITAzienda Unità Sanitaria Locale Della Romagna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Italy, the adoption of a total lockdown has generated almost total suspension of outpatient visits except for emergencies. Even after lockdown, the pandemic fear created additional barriers to access the health services. The aim of our study is to evaluate the economic impact of the lockdown for COVID-19 on public health in Italy, focusing on its effects on diabetic population. MATERIALS AND

methodsWe analyzed the impact of the lockdown on excess mortality and morbidity in the Italian diabetic population during 2020. The analysis was divided into several steps: a quantification of specialist visit reduction, the calculation of excess mortality in the diabetic population, the economic evaluation of the slowdown in the use of innovative diabetic therapies. Furthermore, the impact of the lockdown on the reduction of procedures and follow-up visits in diabetic population was evaluated. The overall impact of the pandemic and lockdown effects on costs and quality of life was then calculated.

resultsDuring 2020, a drop of 28% in patient access has been observed. Diabetic patients recorded a twice higher mortality value compared to general population (20.4% vs 10.2%). The analysis of market data revealed a slowdown in consumption of new antidiabetic therapies (-14%, 27% vs 41%). We estimated an expense of €26.6 million for NHS and a loss of 257 utilities in diabetic population due to the missed benefits related to slowdown in innovative antidiabetic drugs use and non-optimal follow-up and control of diabetes complications. In simulation scenarios, we also estimated an overall expenditure ranging from €38.7 to 94.0 million and a loss of 294-836 utilities.

conclusionDiabetic population paid a high tribute to pandemic and lockdown, both in terms of number of deaths and burden of diabetic complications, together with an overall deterioration of quality of life.

Indexed as

COVID-19diabetes type IIdiabetic complicationseconomic impactquality of life

Identifiers

PMID34163191
PMCPMC8213950
OpenAlexW3168084882

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.