Evidence map›Paper›PMID 34163143›Full record

ArticlePatient preference and adherence2021

Factors of Interest in Extended-Release Buprenorphine: Comparisons Between Incarcerated and Non-Incarcerated Patients with Opioid Use Disorder.

Mathieu Chappuy, Fadi Meroueh, Benoit Trojak, Jérôme Bachellier, Patrick Bendimerad, Margaux Kosim, Peter Hjelmström, Philippe Nubukpo, Georges Brousse, Benjamin Rolland

Open access · goldAbstract read
In one paragraph

Article in Patient preference and adherence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 2 countries.

Mathieu ChappuyService Universitaire d'Addictologie de Lyon (SUAL), CH Le Vinatier, Bron, 69500, France.ORCID 0000-0002-3176-6039
Fadi MerouehUCSA, CHU Lapeyronie, Montpellier, France.
Benoit TrojakService Hospitalo-Universitaire d'Addictologie, CHU de Dijon, Dijon, France.
Jérôme BachellierService Universitaire d'Addictologie de Tours, CHU Bretonneau, Tours, France.
Patrick BendimeradService d'Addictologie, Groupe Hospitalier de La Rochelle-Ré-Aunis, La Rochelle, France.
Margaux KosimConsultations de Médecine-Alcoologie PASS, Groupe Hospitalier Pitié Salpêtrière, Paris, France.
Peter HjelmströmCamurus AB, Ideon Science Park, Lund, Sweden.
Philippe NubukpoService d'Addictologie, Centre Hospitalier Esquirol, Limoges, France.
Georges BrousseService de Psychiatrie B et d'Addictologie, CHU de Clermont-Ferrand, Clermont-Ferrand, France.
Benjamin RollandService Universitaire d'Addictologie de Lyon (SUAL), CH Le Vinatier, Bron, 69500, France.ORCID 0000-0002-8666-3635
Inserm · FRCentre Hospitalier de La Rochelle · FRCentre Hospitalier Universitaire de Tours · FRHôpital Lapeyronie · FRHospices Civils de Lyon · FRIdeon Science Park · SESorbonne Université · FRUniversité Claude Bernard Lyon 1 · FRUniversité Clermont Auvergne · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeExtended-release buprenorphine (XR-BUP) covers a range of formulations of buprenorphine-based treatments for opioid use disorder (OUD) that release the medication over a period of one week, one month, or six months. OUD is particularly prevalent among incarcerated populations, and previous findings have shown that incarcerated subjects were not less interested in XR-BUP than non-incarcerated subjects. However, no study has ever investigated whether the factors of interest in XR-BUP were similar in incarcerated and non-incarcerated populations. PATIENTS AND

methodsWe carried out post-hoc analyses using data from the "AMBRE" survey, which was conducted among 366 individuals with OUD, that were recruited in 68 French addiction settings, including six prison medical centers. The reasons for interest in XR-BUP were compared between incarcerated and non-incarcerated interviewees, using logistic regressions models, which provided raw and adjusted odds ratios (aORs) and 95% confidence intervals (95% CI). Adjustment variables were gender, age category, level of education, and type of current medication for OUD, respectively.

resultsData from 317 participants (ie, 221 non-incarcerated, and 96 incarcerated individuals) were included in the analyses. Adjusted comparisons found that "no longer taking a daily treatment" (aOR= 2.91; 95% CI= 1.21-6.98) and "having a more discreet medication" (aOR= 1.76; 95% CI= 1.01-3.10) were reasons that appealed more to incarcerated participants than to non-incarcerated ones. On the other hand, the potential reduction of withdrawal symptoms (aOR= 0.54; 95% CI= 0.29-0.99) or the risk of misuse (aOR= 0.56; 95% CI= 0.34-0.94) associated with XR-BUP treatment were considered more important by non-incarcerated individuals than by incarcerated ones.

conclusionIncarcerated interviewees were interested in XR-BUP for different reasons than those outside prison. In particular, incarcerated patients were more interested in practicability and discretion features, and less in improving recovery or reducing misuse than non-incarcerated patients.

Indexed as

buprenorphineopioid use disorderpreferencesprison

Identifiers

PMID34163143
PMCPMC8214559
OpenAlexW3170947209

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.