Evidence map›Paper›PMID 34163111›Full record

ReviewWorld journal of gastroenterology2021

Chronic hepatitis B in pregnant women: Current trends and approaches.

Maria Belopolskaya, Viktor Avrutin, Olga Kalinina, Alexander Dmitriev, Denis Gusev

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Comprehensive Interventions in HBV Care: Nursing-Sensitive Approach.Gynecologic and obstetric investigation · 2025
    Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Global elimination of HBV: Is it really achievable?Journal of viral hepatitis · 2024
    Review
  9. Functional cure of chronic hepatitis B-hope or hype?World journal of hepatology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Maria BelopolskayaPolyclinical Department, Botkin's Infectious Disease Hospital, St-Petersburg 195067, Russia.
Viktor AvrutinInstitute for Systems Theory, University of Stuttgart, Stuttgart 70569, Baden-Wurttemberg, Germany.
Olga KalininaFaculty of Biomedical Sciences, Almazov National Medical Research Centre, St-Petersburg 197341, Russia.
Alexander DmitrievDepartment of Molecular Microbiology, Institute of Experimental Medicine, St-Petersburg 197376, Russia.
Denis GusevBotkin's Infectious Disease Hospital, St-Petersburg 195067, Russia.
Botkin Hospital · RUClinical Infectious Disease Hospital named after S.P. Botkin · RUFederal Almazov North-West Medical Research Centre · RUInstitute of Experimental Medicine · RUUniversity of Stuttgart · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic hepatitis B (CHB) is a significant public health problem worldwide. The aim of the present review is to summarize the actual trends in the management of CHB in pregnant women. The prevalence of hepatitis B virus (HBV) infection in pregnant women is usually comparable to that in the general population in the corresponding geographic area. All women have to be screened for hepatitis B surface antigen (HBsAg) during pregnancy. Additional examinations of pregnant women with CHB may include maternal hepatitis B e antigen, HBV viral load, alanine aminotransferase level, and HBsAg level. The management of pregnancy depends on the phase of the HBV infection, which has to be determined before pregnancy. In women of childbearing age with CHB, antiviral therapy can pursue two main goals: Treatment of active CHB, and vertical transmission prevention. During pregnancy, tenofovir is the drug of choice in both cases. A combination of hepatitis B immunoglobulin and vaccine against hepatitis B should be administered within the first 12 h to all infants born to mothers with CHB. In such cases, there are no contraindications to breastfeeding.

Indexed as

Hepatitis BHepatitis B, ChronicPregnancy Complications, InfectiousFemaleHepatitis B e AntigensHepatitis B Surface AntigensHepatitis B virusHumansInfantInfectious Disease Transmission, VerticalPregnancyPregnant PeopleViral LoadHepatitis B e AntigensHepatitis B Surface AntigensAntiviral treatmentChronic hepatitis BHepatitis B viral loadMother-to-child transmissionNewbornsPregnancy

Identifiers

PMID34163111
PMCPMC8218362
OpenAlexW3174333930

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.