Evidence map›Paper›PMID 34163089›Full record

ArticleNature structural & molecular biology2021

Fusion proteins form onco-condensates.

Tanja Mittag, Aseem Z Ansari

Abstract read
PubMed Publisher
In one paragraph

Article in Nature structural & molecular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Fusion protein condensate formation via coiled-coil domains.Protein science : a publication of the Protein Society · 2026
    Article
  2. Article
  3. Article
  4. In search of chemical rationales.Nature chemical biology · 2024
    Article
  5. Review
  6. Article
  7. Review
  8. Function moves biomolecular condensates in phase space.BioEssays : news and reviews in molecular, cellular and developmental biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Tanja MittagDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA. tanja.mittag@stjude.org.ORCID http://orcid.org/0000-0002-1827-3811
Aseem Z AnsariDepartment of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA. aseem.ansari@stjude.org.ORCID http://orcid.org/0000-0003-1432-4498

Funding

Understanding the Sequence and Structural Determinants of Phase Behavior of ALS-Causing ProteinsR01NS121114 · NINDS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Tanja Mittag, ROHIT V PAPPU · 2021 to 2026
$3.8M
Synthetic molecules to stimulate the expression of Frataxin to ameliorate Freidreichs AtaxinR01NS108376 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI ASEEM Z ANSARI · 2018 to 2026
$3.6M
The role of weak multivalent interactions and phase separation in SPOP tumor suppressor functionR01GM112846 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI MITTAG, TANJA · 2015 to 2023
$3.0M
Revealing Masked Specificities of Human Nuclear ReceptorsR01GM120625 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI ANSARI, ASEEM Z · 2016 to 2019
$1.7M
NIGMS NIH HHS R01 GM112846NIGMS NIH HHS R01 GM120625NINDS NIH HHS R01 NS108376NINDS NIH HHS R01 NS121114
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CarcinogenesisHomeodomain ProteinsHumansLeukemiaNeoplasm ProteinsNuclear PoreNuclear Pore Complex ProteinsOncogene Proteins, FusionTranscriptional ActivationTranslocation, Genetichomeobox protein HOXA9Homeodomain ProteinsNeoplasm ProteinsNuclear Pore Complex ProteinsNup98 protein, humanOncogene Proteins, Fusion

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.