Evidence map›Paper›PMID 34162939›Full record

ArticleScientific reports2021

Saccadic suppression in schizophrenia.

Rebekka Lencer, Inga Meyhöfer, Janina Triebsch, Karen Rolfes, Markus Lappe, Tamara Watson

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Basic symptoms of psychosis-from historical foundations to current evidence.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2026
    Review
  3. Article
  4. Perceptual Functioning.Current topics in behavioral neurosciences · 2023
    Article
  5. The impact of visual dysfunctions in recent-onset psychosis and clinical high-risk state for psychosis.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Rebekka LencerInstitute of Translational Psychiatry, University of Münster, Albert-Schweitzer-Campus 1, Geb. A9a, 48149, Münster, Germany. lencer@uni-muenster.de.
Inga MeyhöferInstitute of Translational Psychiatry, University of Münster, Albert-Schweitzer-Campus 1, Geb. A9a, 48149, Münster, Germany.
Janina TriebschInstitute of Psychology, University of Münster, 48149, Münster, Germany.
Karen RolfesInstitute of Translational Psychiatry, University of Münster, Albert-Schweitzer-Campus 1, Geb. A9a, 48149, Münster, Germany.
Markus LappeOtto-Creutzfeldt Center for Cognitive and Behavioral Neuroscience, University of Münster, 48149, Münster, Germany.
Tamara WatsonSchool of Psychology, MARCS Institute for Brain, Behaviour and Development, Western Sydney University, Penrith, NSW, 2751, Australia.
University of Münster · DEWestern Sydney University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

About 40% of schizophrenia patients report discrete visual disturbances which could occur if saccadic suppression, the decrease of visual sensitivity around saccade onset, is impaired. Two mechanisms contribute to saccadic suppression: efference copy processing and backwards masking. Both are reportedly altered in schizophrenia. However, saccadic suppression has not been investigated in schizophrenia. 17 schizophrenia patients and 18 healthy controls performed a saccadic suppression task using a Gabor stimulus with individually adjusted contrast, which was presented within an interval 300 ms around saccade onset. Visual disturbance scores were higher in patients than controls, but saccadic suppression strength and time course were similar in both groups with lower saccadic suppression rates being similarly related to smaller saccade amplitudes. Saccade amplitudes in the saccadic suppression task were reduced in patients, in contrast to unaltered amplitudes during a saccade control task. Notably, smaller saccade amplitudes were related to higher visual disturbances scores in patients. Saccadic suppression performance was unrelated to symptom expression and antipsychotic medication. Unaltered saccadic suppression in patients suggests sufficiently intact efference copy processing and backward masking as required for this task. Instead, visual disturbances in patients may be related to restricted saccadic amplitudes arising from cognitive load while completing a task.

Indexed as

AdultContrast SensitivityFemaleHumansMaleMiddle AgedPhotic StimulationPsychotic DisordersPsychotropic DrugsSaccadesSchizophreniaVision DisordersVisual PerceptionPsychotropic Drugs

Identifiers

PMID34162939
PMCPMC8222214
OpenAlexW3175324277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.