ArticleNature communications2021
Transforming biorefinery designs with 'Plug-In Processes of Lignin' to enable economic waste valorization.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Atom-Economic Synthesis and Morphology-Dependent Marine Biodegradation Behavior of 2‑Pyrone-4,6-Dicarboxylic Acid-Based Polyesteramide.Polymer science & technology (Washington, D.C.) · 2026Article
- Reimagining Lignin Valorization: Synthetic Biology-Enabled Sustainable Aromatic Carbon Biomanufacturing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Synergistic pretreatment: hybrid strategies for maximum lignocellulose valorization.Biodegradation · 2026Review
- Advances in Integrated Lignin Valorization Pathways for Sustainable Biorefineries.Molecules (Basel, Switzerland) · 2026Review
- Remediation and upcycling of microplastics by algae with wastewater nutrient removal and bioproduction potential.Nature communications · 2025Article
- Multiscale metabolic engineering in biological lignin valorization.Innovation (Cambridge (Mass.)) · 2025Review
- Valorization of Lignin and Its Derived Molecules by Electrocatalytic Oxidation.ACS sustainable chemistry & engineering · 2025Review
- Antimicrobial, photodegradation and BioReRAM applications of multifaceted green zinc oxide nanoparticles synthesized using coffee leaves extract.Scientific reports · 2025Article
- Storage-Induced Collapse of Lignin Macromolecular Structure and Its Impacts on the Biorefinery.ACS sustainable chemistry & engineering · 2025Article
- Soda lignin as a sustainable photosensitive component for conventional and controlled radical photopolymerization.Communications chemistry · 2025Article
- Metagenomic Analysis of Pulp and Paper Wastes and Prospects for Their Self-purification.Current microbiology · 2025Article
- Lignin valorization to bioplastics with an aromatic hub metabolite-based autoregulation system.Nature communications · 2024Article
- Blue valorization of lignin-derived monomers via reprogramming marine bacteriumApplied and environmental microbiology · 2024Article
- ATP biosensor reveals microbial energetic dynamics and facilitates bioproduction.Nature communications · 2024Article
- Synthetically-primed adaptation of Pseudomonas putida to a non-native substrate D-xylose.Nature communications · 2024Article
- Aqueous amine enables sustainable monosaccharide, monophenol, and pyridine base coproduction in lignocellulosic biorefineries.Nature communications · 2024Article
- Pharmaceutical applications of lignin-derived chemicals and lignin-based materials: linking lignin source and processing with clinical indication.Biomass conversion and biorefinery · 2024Review
- Review
- Dissolving Kraft Pulp Production and Xylooligosaccharide Coproduction: Effect of Pre-Hydrolysis Conditions.ACS omega · 2023Article
- Bioresource Upgrade for Sustainable Energy, Environment, and Biomedicine.Nano-micro letters · 2023Review
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biological lignin valorization has emerged as a major solution for sustainable and cost-effective biorefineries. However, current biorefineries yield lignin with inadequate fractionation for bioconversion, yet substantial changes of these biorefinery designs to focus on lignin could jeopardize carbohydrate efficiency and increase capital costs. We resolve the dilemma by designing 'plug-in processes of lignin' with the integration of leading pretreatment technologies. Substantial improvement of lignin bioconversion and synergistic enhancement of carbohydrate processing are achieved by solubilizing lignin via lowering molecular weight and increasing hydrophilic groups, addressing the dilemma of lignin- or carbohydrate-first scenarios. The plug-in processes of lignin could enable minimum polyhydroxyalkanoate selling price at as low as $6.18/kg. The results highlight the potential to achieve commercial production of polyhydroxyalkanoates as a co-product of cellulosic ethanol. Here, we show that the plug-in processes of lignin could transform biorefinery design toward sustainability by promoting carbon efficiency and optimizing the total capital cost.
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