Evidence map›Paper›PMID 34162604›Full record

ArticleBMJ case reports2021

Intravascular lymphoma presenting with hypoxaemia, platypnoea and lactic acidosis.

Pierre Englert, Sophie Levy, Marc Vekemans, Virginie De Wilde

Open access · hybridAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Pierre EnglertInternal Medicine, Erasmus Hospital, Brussels, Belgium englert.pierre@gmail.com.
Sophie LevyGeriatrics, Brugmann University Hospital, Brussels, Belgium.
Marc VekemansInternal Medicine, Iris Ziekenhuizen Zuid, Brussels, Belgium.
Virginie De WildeHaematology, Erasmus Hospital, Brussels, Belgium.
Erasmus Hospital · BECentre Hospitalier Universitaire Brugmann · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intravascular large B-cell lymphoma (IVLBCL) is an aggressive and rare type of diffuse extranodal B-cell lymphoma. Diagnosis and treatment are challenging and clinical presentation is variable. Physicians should be aware of this rare but life-threatening lymphoma without adenopathy and treatment should be promptly started. We describe the case of a 70-year-old woman who presented with general malaise, acute dyspnoea, platypnoea and lactic acidosis. Echocardiography revealed an extracardiac shunt, the cause of her orthodeoxia. The patient developed rapid liver failure and underwent liver biopsy. Anatomopathological findings suggested IVLBCL, non-germinal center type. She achieved complete remission after rituximab, cyclophosphamide, doxorubicin, vincristine, methylprednisolone chemotherapy but relapsed 1 year after initial presentation with multiple organ involvement. The patient's relapsed disease was treated with rituximab, iphosphamide, carboplatin, etoposide and she is still in complete remission 2 years later.

Indexed as

Acidosis, LacticLymphoma, Large B-Cell, DiffuseAgedAntineoplastic Combined Chemotherapy ProtocolsCyclophosphamideDoxorubicinDyspneaFemaleHumansHypoxiaPrednisoneRituximabVincristineCyclophosphamideDoxorubicinPrednisoneRituximabVincristinehaematology (incl blood transfusion)liver diseasemalignant and benign haematologyrespiratory medicine

Identifiers

PMID34162604
PMCPMC8230943
OpenAlexW3176213385

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.