ReviewJournal of pediatric urology2021
EAU-ESPU pediatric urology guidelines on testicular tumors in prepubertal boys.
Review in Journal of pediatric urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 26 citations in OpenAlex.
- Develop and validate nomogram to predict cancer-specific survival for patients with testicular yolk sac tumors.Frontiers in public health · 2022Trial
- Management of andrological disorders from childhood and adolescence to transition age: guidelines from the Italian Society of Andrology and Sexual Medicine (SIAMS) in collaboration with the Italian Society for Pediatric Endocrinology and Diabetology (SIEDP) - part-2.Journal of endocrinological investigation · 2026Article
- Establishment and characterization of a testicular yolk sac tumor PDX model.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Article
- Comparative Molecular and Genetic Landscape of Gonadal Germ Cell Tumors: Insights from Testicular and Ovarian Neoplasms.Cancers · 2026Review
- Yolk sac tumor after post-detorsion changes in a torsed undescended testis: a case report.Translational andrology and urology · 2026Article
- Multidisciplinary evaluation improves prevalence of testis-sparing surgery in children with testicular benign tumors: a cross-section study.BMC cancer · 2026Article
- Testis-sparing surgery for Leydig cell tumor in children: long-term results of a multicentric retrospective cohort study.BMC urology · 2026Article
- Diagnosis, treatment, and long-term follow-up of a 13-year-old boy with a testicular mixed germ cell tumor (yolk sac tumor and embryonal carcinoma): a case report and literature review.Frontiers in pediatrics · 2026Article
- Article
- A rare finding of testicular epidermoid keratinized cyst in a prepubertal boy: case report and management standardization.Journal of ultrasound · 2025Article
- Diagnostic features of pediatric testicular yolk sac tumors: a 13-year retrospective analysis.World journal of surgical oncology · 2024Article
- Rare pediatric synchronous bilateral testicular germ cell tumors of different pathological types: a case report.Frontiers in pediatrics · 2024Article
- Testicular tumor arising from an intra-abdominal undescended testis in a 1-year-old child: a case report and literature review.Frontiers in pediatrics · 2023Article
- Review
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Authors and funding
11 authors at 8 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTesticular tumors in prepubertal boys account for 1-2% of all solid pediatric tumors. They have a lower incidence, a different histologic distribution and are more often benign compared to testicular tumors in the adolescent and adult group. This fundamental difference should also lead to a different approach and treatment.
objectiveTo provide a guideline for diagnosis and treatment options in prepubertal boys with a testicular mass.
methodA structured literature search and review for testicular tumors in prepubertal boys was performed. All English abstracts up to the end of 2019 were screened, and relevant papers were obtained to create the guideline.
resultsA painless scrotal mass is the most common clinical presentation. For evaluation, high resolution ultrasound has a detection rate of almost 100%, alpha-fetoprotein is a tumor marker, however, is age dependent. Human chorionic gonadotropin (HCG) was not a tumor marker for testis tumors in prepubertal boys.
conclusionBased on a summary of the literature on prepubertal testis tumors, the 2021 EAU guidelines on Pediatric Urology recommend a partial orchiectomy as the primary approach in tumors with a favorable preoperative ultrasound diagnosis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.