Evidence map›Paper›PMID 34162445›Full record

ArticleTropical medicine and health2021

The use of antibiotics in COVID-19 management: a rapid review of national treatment guidelines in 10 African countries.

Yusuff Adebayo Adebisi, Nafisat Dasola Jimoh, Isaac Olushola Ogunkola, Theogene Uwizeyimana, Alaka Hassan Olayemi, Nelson Ashinedu Ukor, Don Eliseo Lucero-Prisno

Open access · goldAbstract readLetter
In one paragraph

Article in Tropical medicine and health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 2 pooled it
17.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 2 syntheses or guidelines pooled it, 150 citations in OpenAlex.

  1. Pooled it
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  4. Dramatic increase in consumption of antibiotics in Colombia, 2020-2023Biomedica : revista del Instituto Nacional de Salud · 2026
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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 4 countries.

Yusuff Adebayo AdebisiFaculty of Pharmacy, University of Ibadan, Ibadan, Nigeria.
Nafisat Dasola JimohFederal University of Technology Minna, Minna, Nigeria.
Isaac Olushola OgunkolaDepartment of Public Health, University of Calabar, Calabar, Nigeria.
Theogene UwizeyimanaDepartment of Public Health, Mount Kenya University Rwanda, Kigali, Rwanda. uwizeyimanatheogene@gmail.com.ORCID http://orcid.org/0000-0002-1360-0211
Alaka Hassan OlayemiDepartment of Microbiology, Obafemi Awolowo University, Ile-Ife, Nigeria.
Nelson Ashinedu UkorFaculty of Pharmacy, University of Port Harcourt, Choba, Nigeria.
Don Eliseo Lucero-PrisnoDepartment of Global Health and Development, London School of Hygiene and Tropical Medicine, London, UK.
Federal University of Technology Minna · NGLondon School of Hygiene & Tropical Medicine · GBMount Kenya University · KEObafemi Awolowo University · NGUniversity of Calabar · NGUniversity of Ibadan · NGUniversity of Port Harcourt · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance is a hidden threat lurking behind the COVID-19 pandemic which has claimed thousands of lives prior to the emergence of the global outbreak. With a pandemic on the scale of COVID-19, antimicrobial resistance has the potential to become a double-edged sword with the overuse of antibiotics having the potential of taking us back to the pre-antibiotic era. Antimicrobial resistance is majorly attributed to widespread and unnecessary use of antibiotics, among other causes, which has facilitated the emergence and spread of resistant pathogens. Our study aimed to conduct a rapid review of national treatment guidelines for COVID-19 in 10 African countries (Ghana, Kenya, Uganda, Nigeria, South Africa, Zimbabwe, Botswana, Liberia, Ethiopia, and Rwanda) and examined its implication for antimicrobial resistance response on the continent. Our findings revealed that various antibiotics, such as azithromycin, doxycycline, clarithromycin, ceftriaxone, erythromycin, amoxicillin, amoxicillin-clavulanic acid, ampicillin, gentamicin, benzylpenicillin, piperacillin/tazobactam, ciprofloxacin, ceftazidime, cefepime, vancomycin, meropenem, and cefuroxime among others, were recommended for use in the management of COVID-19. This is worrisome in that COVID-19 is a viral disease and only a few COVID-19 patients would have bacterial co-infection. Our study highlighted the need to emphasize prudent and judicious use of antibiotics in the management of COVID-19 in Africa.

Indexed as

AfricaAntibiotic resistanceAntimicrobial resistanceClinical case managementCOVID-19Pandemic

Identifiers

PMID34162445
PMCPMC8220112
OpenAlexW3175151568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.