Evidence map›Paper›PMID 34162380›Full record

ArticleWorld journal of surgical oncology2021

Clinical analysis of 48 cases of malignant superior vena cava syndrome.

Manzhen Sun, Xiaoli Chen, Hongfei Li, Xudong Zhang, Xiaofei Wang, Ruipan Zheng, Guowen Li, Lin Wang, Dianyuan Li

Abstract read
In one paragraph

Article in World journal of surgical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Emergency radiation therapy in modern-day practice: Now or never, or never again ?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Manzhen SunSchool of Basic Medical Sciences, Zhengzhou University, No. 100 Science Avenue, Zhengzhou, 450000, Henan Province, China.
Xiaoli ChenSchool of Basic Medical Sciences, Zhengzhou University, No. 100 Science Avenue, Zhengzhou, 450000, Henan Province, China.
Hongfei LiRadiotherapy Inpatient Ward II, The First Affiliated Hospital of Zhengzhou University, No. 1 Eastern Jianshe Road, Zhengzhou, 450052, Henan Province, China.
Xudong ZhangRadiotherapy Inpatient Ward II, The First Affiliated Hospital of Zhengzhou University, No. 1 Eastern Jianshe Road, Zhengzhou, 450052, Henan Province, China.
Xiaofei WangRadiotherapy Inpatient Ward II, The First Affiliated Hospital of Zhengzhou University, No. 1 Eastern Jianshe Road, Zhengzhou, 450052, Henan Province, China.
Ruipan ZhengRadiotherapy Inpatient Ward II, The First Affiliated Hospital of Zhengzhou University, No. 1 Eastern Jianshe Road, Zhengzhou, 450052, Henan Province, China.
Guowen LiRadiotherapy Inpatient Ward II, The First Affiliated Hospital of Zhengzhou University, No. 1 Eastern Jianshe Road, Zhengzhou, 450052, Henan Province, China.
Lin Wang *Radiotherapy Inpatient Ward II, The First Affiliated Hospital of Zhengzhou University, No. 1 Eastern Jianshe Road, Zhengzhou, 450052, Henan Province, China. linwang_zzu@163.com.
Dianyuan Li *School of Basic Medical Sciences, Zhengzhou University, No. 100 Science Avenue, Zhengzhou, 450000, Henan Province, China. dianyuanli58@163.com.

Funding

Medical Science and Technology Key Project of Henan Province SB201901021
6 · The paper itself

Abstract

backgroundThe aim of our study was to observe and compare the curative effect of radiotherapy, chemotherapy, and combined radiotherapy and chemotherapy, as well as comprehensive treatment on superior vena cava syndrome (SVCS) caused by malignant etiology.

methodsA total of 48 patients with malignant SVCS admitted to our hospital from 2015 to 2020 were selected in this study. According to the different treatment methods, they were divided into radiotherapy group (group 1, 10 cases), chemotherapy group (group 2, 8 cases), combined radiotherapy and chemotherapy group (group 3, 22 cases), and comprehensive treatment group (group 4, 8 cases).

resultsThere were no significant differences in efficacy and side effects among the four groups (all P > 0.05). Group 4 (median survival time of 36 months) could provide longer survival time than groups 1, 2, and 3 (median survival time of 10 months, 13.5 months, and 12 months, respectively).

conclusionsFor patients with severe symptoms or good prognosis, comprehensive treatment could be selected to improve the quality of life and prolong the survival period; for patients with mild symptoms, radiotherapy, chemotherapy, or combined radiotherapy and chemotherapy could also reduce the symptoms of SVCS and treat tumor lesions.

Indexed as

Lung NeoplasmsSuperior Vena Cava SyndromeHumansPrognosisQuality of LifeStentsChemotherapyComprehensive treatmentMalignant etiologyRadiotherapySuperior vena cava syndrome

Identifiers

PMID34162380
PMCPMC8223363

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.